874522-46-0 Usage
Uses
Used in Organic Synthesis:
2,4-dibromo-benzoic acid amide is used as a building block in organic synthesis for the creation of various pharmaceuticals and agrochemicals. Its unique chemical properties make it a valuable component in the synthesis of new compounds with potential applications in different industries.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2,4-dibromo-benzoic acid amide is employed as a key intermediate for the development of new drug candidates. Its structural features allow for the design and synthesis of novel therapeutic agents with improved pharmacological properties.
Used in Laboratory Research:
2,4-dibromo-benzoic acid amide is utilized as a reagent in laboratory research for the synthesis of novel compounds. It aids in the study of organic reactions and contributes to the advancement of chemical knowledge and the discovery of new chemical entities.
Used in Pharmaceutical Industry:
2,4-dibromo-benzoic acid amide is used as a precursor in the pharmaceutical industry for the production of various drugs. Its presence in the synthesis process allows for the creation of medications with specific therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical industry, 2,4-dibromo-benzoic acid amide is employed as a starting material for the synthesis of pesticides and other agrochemical products. Its role in the development of these products contributes to the enhancement of crop protection and agricultural yield.
Check Digit Verification of cas no
The CAS Registry Mumber 874522-46-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,4,5,2 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 874522-46:
(8*8)+(7*7)+(6*4)+(5*5)+(4*2)+(3*2)+(2*4)+(1*6)=190
190 % 10 = 0
So 874522-46-0 is a valid CAS Registry Number.
874522-46-0Relevant academic research and scientific papers
Acid-promoted palladium(II)-catalyzed ortho-halogenation of primary benzamides: En route to halo-arenes
Jaiswal, Yogesh,Kumar, Amit
, (2019/08/26)
Br?nsted acid-promoted palladium(II)-catalyzed regioselective installation of halogens (Br, Cl, and I) to the aromatic ring of benzamide derivatives has been achieved using primary amides. A wide variety of benzamides were compatible under established conditions to afford the halogenated products without installing any external auxiliary. Mild reaction conditions, use of primary amide as a directing group, external additive-free conditions, and gram-scale reaction are some appealing features of this protocol. Detailed experimental results revealed that Br?nsted acid plays a critical role in this transformation.
BENZAZEPINE DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF
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Paragraph 0166; 0167, (2019/03/29)
Disclosed are a benzazepine derivative, a preparation method, a pharmaceutical composition and the use thereof. A compound as shown in formula (I) of the present invention, and an isomer, a prodrug, a stable isotope derivative or a pharmaceutically acceptable salt thereof have the following structure. The benzazepine derivative of the present invention has a good regulation effect on the TLR family and the related signalling pathway, and in particular, has a good regulation effect on TLR8, can effectively treat, relieve and/or prevent various diseases mediated by TLR family and the TLR-related signalling pathway, and in particular, can effectively treat, relieve and/or prevent various diseases mediated by TLR8, such as cancers, autoimmune diseases, infections, inflammations, transplantation rejections, graft-versus-host diseases, etc.
