875145-55-4

Basic information

• Product Name: Acetamide, N-(3-fluoro-4-iodo-2-methylphenyl)-
• CAS NO: 875145-55-4
• Molecular Formula: C9H9FINO
• Molecular Weight: 293.079
• Mol File: 875145-55-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetamide, N-(3-fluoro-4-iodo-2-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-(3-fluoro-4-iodo-2-methylphenyl)-(875145-55-4)
• EPA Substance Registry System: Acetamide, N-(3-fluoro-4-iodo-2-methylphenyl)-(875145-55-4)

Safety Data

• Hazardous Substances Data: 875145-55-4(Hazardous Substances Data)

Upstream product

• 443-86-7 3-fluoro-2-methylaniline 
• 75-36-5 acetyl chloride 
• 329927-16-4 2-fluoro-3-methyl-4-aminophenyl iodide 

Downstream Products

• 194804-84-7 2-fluoro-3-methyl-4-aminobenzoic acid 
• 1364740-54-4 C₂₂H₁₃ClF₅NO₃ 
• 1364740-36-2 C₂₄H₁₃ClF₅NO₄ 
• 875145-49-6 2-fluoro-3-methyl-4-(acetyl)aminobenzoic acid 
• 322-33-8 N-(3-fluoro-2-methylphenyl)acetamide 

Relevant articles and documents

Practical synthesis of a benzophenone-based NNRT inhibitor of HIV-1

A convergent synthesis of NNRTI 1 is described. The key step involves a direct coupling of acid chloride 4 with Grignard reagent 11 in the presence of bis[2-(N,N-dimethylamino)ethyl] ether that moderates the reactivity of the Grignard reagent to give benzophenone 7. An efficient 2-step process for the preparation of 2-fluoro-3-methyl-4-aminobenzoic acid (3) is also described.