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322-33-8

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322-33-8 Usage

General Description

N-(3-Fluoro-2-methylphenyl)acetamide is a chemical compound with the molecular formula C9H10FNO. It is an amide derivative of 3-fluoro-2-methylphenylacetic acid and is commonly used in research and pharmaceutical applications. N-(3-FLUORO-2-METHYLPHENYL)ACETAMIDE is known for its analgesic and anti-inflammatory properties, and it has been studied for its potential use in the development of new drugs for pain management. N-(3-Fluoro-2-methylphenyl)acetamide is also used as a building block in organic synthesis and as a reagent in chemical reactions. As a result of its diverse applications, this compound is of interest to scientists and researchers in the fields of medicinal chemistry, pharmacology, and chemical synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 322-33-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,2 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 322-33:
(5*3)+(4*2)+(3*2)+(2*3)+(1*3)=38
38 % 10 = 8
So 322-33-8 is a valid CAS Registry Number.

322-33-8Relevant articles and documents

Copper-(II) Catalyzed N-Formylation and N-Acylation of Aromatic, Aliphatic, and Heterocyclic Amines and a Preventive Study in the C-N Cross Coupling of Amines with Aryl Halides

Sonawane, Rahul B.,Rasal, Nishant K.,Bhange, Dattatraya S.,Jagtap, Sangeeta V.

, p. 3907 - 3913 (2018/09/12)

A Cu-(II) catalyzed N-formylation and N-acylation of amines with moderate to excellent yields, using N, N-dimethyl formamide (DMF) and N, N-dimethyl acetamide (DMA) as a formyl and acylating sources in the presence of 1,2,4-triazole is reported. This novel, highly efficient and simple protocol shows broad substrate scope for aliphatic, aromatic, and heterocyclic amines. In addition, the conditions to prevent N-formylation and N-acylation impurities in the C?N cross coupling of amines and aryl halides are described typically when DMF and DMA are used as solvents, with various catalysts, ligands, and bases.

Practical synthesis of a benzophenone-based NNRT inhibitor of HIV-1

Wang, Xiao-Jun,Zhang, Li,Sun, Xiufeng,Lee, Heewon,Krishnamurthy, Dhileepkumar,O'Meara, Jeff A.,Landry, Serge,Yoakim, Christiane,Simoneau, Bruno,Yee, Nathan K.,Senanayake, Chris H.

, p. 561 - 566 (2012/07/03)

A convergent synthesis of NNRTI 1 is described. The key step involves a direct coupling of acid chloride 4 with Grignard reagent 11 in the presence of bis[2-(N,N-dimethylamino)ethyl] ether that moderates the reactivity of the Grignard reagent to give benzophenone 7. An efficient 2-step process for the preparation of 2-fluoro-3-methyl-4-aminobenzoic acid (3) is also described.

Enzymatic substrates derived from phenoxazinone and their use as developer in detection of microorganisms with peptidase activity

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Page/Page column 18-19, (2009/12/07)

Novel enzymatic substrates of the general formula below: reaction media containing the same and their use for detecting and/or identifying and/or quantifying microorganisms expressing at least one peptidase activity.

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