875296-12-1Relevant articles and documents
HIV integrase inhibitors with nucleobase scaffolds: Discovery of a highly potent anti-HIV agent
Nair, Vasu,Chi, Guochen,Ptak, Roger,Neamati, Nouri
, p. 445 - 447 (2007/10/03)
HIV integrase is essential for HIV replication. However, there are currently no integrase inhibitors in clinical use for AIDS. We have discovered a conceptually new β-diketo acid that is a powerful inhibitor of both the 3′-processing and strand transfer s