87568-46-5

Basic information

• Product Name: Carbamic acid, [1-(4-methoxyphenyl)-2-oxo-3-azetidinyl]-, phenylmethyl ester
• CAS NO: 87568-46-5
• Molecular Formula: C18H18N2O4
• Molecular Weight: 326.352
• Mol File: 87568-46-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [1-(4-methoxyphenyl)-2-oxo-3-azetidinyl]-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [1-(4-methoxyphenyl)-2-oxo-3-azetidinyl]-, phenylmethyl ester(87568-46-5)
• EPA Substance Registry System: Carbamic acid, [1-(4-methoxyphenyl)-2-oxo-3-azetidinyl]-, phenylmethyl ester(87568-46-5)

Safety Data

• Hazardous Substances Data: 87568-46-5(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 87568-45-4 3-amino-1-(p-methoxyphenyl)azetidin-2-one 
• 87568-42-1 1-(p-methoxyphenyl)-3-methyl-3-(phenylsulfinyl)azetidin-2-one 
• 87568-30-7 1-(p-methoxyphenyl)-3-methyl-3-(phenylthio)azetidin-2-one 
• 87568-44-3 1-(p-methoxyphenyl)azetidin-2-one 3-oxime 
• 87568-43-2 1-(4'-methoxyphenyl)-azetidin-2,3-dione 
• 7274-71-7 N-(4-methoxyphenyl)-2-methylacrylamide 
• 69193-56-2 1-(4-methoxyphenyl)-3-methylideneazetidin-2-one 
• 104-94-9 4-methoxy-aniline 
• 1145-80-8 N-(benzyloxycarbonyl)-L-serine 

Downstream Products

• 1619921-89-9 benzyl N-methyl-N-[(S)-1-(4-methoxyphenyl)-2-oxo-azetidin-3-yl]carbamate 
• 59511-72-7 (S)-(2-Oxo-3-azetidinyl)carbamic acid,phenylmethyl ester 
• 1619921-90-2 benzyl N-methyl-N-[(S)-2-oxoazetidin-3-yl]carbamate 
• 80082-81-1 benzyl N-[(3S)-2-oxoazetidin-3-yl]carbamate 

Relevant articles and documents

CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS

Described herein are compounds and pharmaceutical compositions which inhibit N-acylethanolamine acid amidase (NAAA). Described herein are methods for synthesizing the compounds set forth herein and methods for formulating these compounds as pharmaceutical compositions which include these compounds. Also described herein are methods of inhibiting NAAA in order to sustain the levels of palmitoylethanolamide (PEA) and other N-acylethanolamines (NAE) that are substrates for NAAA, in conditions characterized by reduced concentrations of NAE. Also, described here are methods of treating and ameliorating pain, inflammation, inflammatory diseases, and other disorders in which modulation of fatty acid ethanolamides is clinically or therapeutically relevant or in which decreased levels of NAE are associated with the disorder.

Design and reactivity of organic functional groups - utility of imidazolylsulfonates in the synthesis of monobactams and 3-amino nocardicinic acid

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Synthesis of β-lactam antibiotics by the sulfeno-cycloamination

A novel efficient beta -lactam synthesis was achieved by two successive processes (sulfeno-cycloamination), addition of phenysulfenyl chloride to alpha , beta -unsaturated amides followed by base treatment. Key synthetic intermediates of monobactams and nocardicin derivatives were obtained via this method. construction of the 1-carbapenam ring system by the sulfenocycloamination is also described.