876181-53-2

Upstream product

• 158110-04-4 (2S)-1,2-epoxy-5-benzyloxy-pentane 
• 112482-35-6 1-(benzyloxy)-4,5-epoxypentane 
• 127793-67-3 (S)‐7‐(benzyloxy)hept‐1‐en‐4‐ol 
• 292638-85-8 acrylic acid methyl ester 
• 75-09-2 dichloromethane 
• 5470-84-8 4-benzyloxybutanal 

Downstream Products

• 1435478-29-7 C₂₃H₄₁NO₄Si 
• 1435478-32-2 C₂₃H₃₈O₃Si 
• 915141-66-1 (2R,5S,6R,7R)-1-[(2S,4S,6S)-6-(3-Benzyloxy-propyl)-2-phenyl-[1,3]dioxan-4-yl]-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-octan-4-one 
• 899827-95-3 (2S,5R,6R,7R)-1-[(2S,4S,6S)-6-(3-Benzyloxy-propyl)-2-phenyl-[1,3]dioxan-4-yl]-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-octan-4-ol 
• 915141-54-7 (2R,5S,6R,7R)-1-[(2S,4R,6S)-6-(3-Benzyloxy-propyl)-2-phenyl-[1,3]dioxan-4-yl]-8-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-6-(4-methoxy-benzyloxy)-5,7-dimethyl-octan-4-one 
• 915141-48-9 2-[(2S,4S,6S)-6-(3-benzyloxy-propyl)-2-phenyl-1,3-dioxan-4-yl]acetaldehyde 
• 915141-46-7 [(2S,4S,6S)-6-(3-Benzyloxy-propyl)-2-phenyl-[1,3]dioxan-4-yl]-acetic acid methyl ester 

Relevant academic research and scientific papers

Total synthesis and biological evaluation of (-)-exiguolide analogues: Importance of the macrocyclic backbone

(-)-Exiguolide (1), isolated from the marine sponge Geodia exigua, has been shown to inhibit the growth of the A549 human lung adenocarcinoma and NCI-H460 human lung large cell carcinoma cells in vitro. In this study, we synthesized structural analogues o

Enantioselective synthesis of the C1-C15 fragment of dolabelide C

A synthesis of the C1-C15 fragment of dolabelide C is reported. The key step is a diastereoselective Mukaiyama aldol reaction to form the C6-C7 bond, followed by reduction and deoxygenation of the carbonyl group at C5. The trisubstituted vinyl iodide is i

A highly enantioselective one-pot synthesis of homoallylic alcohols via tandem asymmetric allyl transfer/olefin cross metathesis

A highly enantioselective one-pot synthesis of linear homoallylic alcohols with terminal ester functionality has been achieved. The reactions were controlled by ordered addition of reagents and catalysts, ensuring complete consumption of aldehyde. The synthetic utility of this strategy has been demonstrated in a short synthesis of a low boiling point intermediate for grahamimycin A.