87638-40-2

Upstream product

• 87580-09-4 (5S*,6R*)-methyl 7,9-dibromo-8-methoxy-6-oxo-1-oxa-2-azaspiro<4.5>deca-2,7,9-triene-3-carboxylate 
• 110-60-1 1,4-diaminobutane 
• 66333-92-4 1,4-bis-(7,9-dibromo-8-methoxy-10-oxo-1-oxa-2-aza-spiro[4.5]deca-2,6,8-triene-3-carbonylamino)-butane 
• 184777-86-4 methyl 2-benzyloxyimino-3-(2'-benzyloxy-3,5-dibromo-4-methoxyphenyl)propionate 
• 212688-07-8 methyl (2-hydroxy-4-methoxyphenyl)acetate 
• 28687-76-5 3-(3,5-Dibromo-2-hydroxy-4-methoxy-phenyl)-N-(4-{3-(3,5-dibromo-2-hydroxy-4-methoxy-phenyl)-2-[(E)-hydroxyimino]-propionylamino}-butyl)-2-[(E)-hydroxyimino]-propionamide 
• 35353-87-8 methyl (3,5-dibromo-2-hydroxy-4-methoxyphenyl)acetate 
• 87580-08-3 methyl 7,9-dibromo-8-methoxy-6-oxo-1-oxa-2-azaspiro<4.5>deca-2,7,9-triene-3-carboxylate 
• 87580-07-2 methyl 2-hydroxyimino-3-(3,5-dibromo-2-hydroxy-4-methoxyphenyl)propionate 
• 28687-76-5 N,N'-bis<3-(3,5-dibromo-2-hydroxy-4-methoxyphenyl)-2-hydroxyiminopropionyl>-1,4-butanediamine 
• 212698-13-0 3-[3,5-Dibromo-4-methoxy-2-(4-methoxy-benzyloxy)-phenyl]-N-(4-{3-[3,5-dibromo-4-methoxy-2-(4-methoxy-benzyloxy)-phenyl]-2-[(E)-hydroxyimino]-propionylamino}-butyl)-2-[(E)-hydroxyimino]-propionamide 
• 212688-12-5 3-[3,5-Dibromo-4-methoxy-2-(4-methoxy-benzyloxy)-phenyl]-N-(4-{3-[3,5-dibromo-4-methoxy-2-(4-methoxy-benzyloxy)-phenyl]-2-oxo-propionylamino}-butyl)-2-oxo-propionamide 
• 212688-10-3 4-[3,5-Dibromo-4-methoxy-2-(4-methoxy-benzyloxy)-phenyl]-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-butyronitrile 
• 212688-08-9 methyl [3,5-dibromo-2-(p-methoxybenzyloxy)-4-methoxyphenyl]acetate 

Relevant academic research and scientific papers

Total synthesis, structural revision, and biological evaluation of calafianin, a marine spiroisoxazoline from the sponge, Aplysina gerardogreeni

The reported structure of the natural calafianin (1) and its isomer in the epoxide region 13 were successfully synthesized through the cis- and trans-spiroisoxazoline compounds, which were produced by electrochemical oxidation of the hydroxyimino-phenol d

Synthesis and structural revision of calafianin, a member of the spiroisoxazole family isolated from the marine sponge, Aplysina gerardogreeni

Calafianin 1 was successfully synthesized by employing a spiroisoxazoline compound, which was produced by electrochemical oxidation of the oximino-phenol derivative 7 followed by reduction. This investigation revealed a structural revision of 1, the trans

Syntheses of the marine metabolites verongamine, hemibastadin-2, and aerothionin using the cyano ylide coupling methodology

Syntheses of the marine metabolites verongamine, hemibastadin-2, and aerothionin have been accomplished by a methodology involving the conversion of a carboxylic acid to an acyl cyano phosphorane which may be oxidized to an α,β-diketo nitrile. This strong

Total syntheses of (±)-aerothionin, (±)-homoaerothionin, and (±)-aerophobin-1

(±)-Aerothionin, (±)-homoaerothionin, and (±)-aerophobin-1 have been successfully synthesized using phenolic oxidation of the methyl pyruvate oxime derivative with thallium(III) trifluoroacetate as a key step. The stereostructure of aerophobin-2 has been also established by comparison of the 1H NMR spectrum with those of related compounds.

TOTAL SYNTHESES OF (+/-)-AEROTHIONIN AND (+/-)-HOMOAEROTHIONIN

Both aerothionin and homoaerothionin, the novel metabolites of the sponges Aplysina aerophoba, A. fistularis and Verongia thiona, have been synthesized in racemic form.