876392-11-9

Basic information

• Product Name: 2-Pentenoic acid, 5-[(2-ethenylphenyl)[(4-methylphenyl)sulfonyl]amino]-, methyl ester, (2E)-
• CAS NO: 876392-11-9
• Molecular Formula: C21H23NO4S
• Molecular Weight: 385.484
• Mol File: 876392-11-9.mol

Chemical Properties

• CAS DataBase Reference: 2-Pentenoic acid, 5-[(2-ethenylphenyl)[(4-methylphenyl)sulfonyl]amino]-, methyl ester, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentenoic acid, 5-[(2-ethenylphenyl)[(4-methylphenyl)sulfonyl]amino]-, methyl ester, (2E)-(876392-11-9)
• EPA Substance Registry System: 2-Pentenoic acid, 5-[(2-ethenylphenyl)[(4-methylphenyl)sulfonyl]amino]-, methyl ester, (2E)-(876392-11-9)

Safety Data

• Hazardous Substances Data: 876392-11-9(Hazardous Substances Data)

Upstream product

• 30765-95-8 N-p-toluenesulfonyl-2-vinylaniline 
• 62592-80-7 methyl trans-5-hydroxy-2-pentenoate 

Downstream Products

• 894810-76-5 3-methylene-2-pent-4-enyl-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-indole 
• 876392-15-3 N-(p-toluenesulfonyl)-2-(3-(methoxycarbonyl)propyl)-3-methylene-2,3-dihydroindole 
• 876392-17-5 4-(N-(p-toluenesulfonyl)-3-methylene-2,3-dihydroindol-2-yl)butanal 
• 894810-73-2 N-(4-(methoxycarbonyl)-1-butenyl)-N-(p-toluenesulfonyl)-2-ethenylaniline 

Relevant articles and documents

Synthesis of the putative structure of fistulosin using the ruthenium-catalyzed cycloisomerization of diene

Fistulosin 1, which was isolated from the root of the Welsh onion, is a novel indole alkaloid that has antifungal activity. The first total synthesis of the reported structure of fistulosin using our cycloisomerization of diene is described.

Development of isomerization and cycloisomerization with use of a ruthenium hydride with N-heterocyclic carbene and its application to the synthesis of heterocycles

A pure ruthenium hydride complex with N-heterocyclic carbene (NHC) ligand was efficiently generated from the reaction of a second-generation Grubbs ruthenium catalyst with vinyloxytrimethylsilane and unambiguously characterized. This ruthenium hydride complex showed high catalytic activity for the selective isomerization of terminal olefin and for the cycloisomerization of 1,6-dienes. These reactions of N-allyl-o-vinylaniline lead to novel synthetic methods for heterocycles such as indoles and 3-methylene-2,3-dihydroindoles, which are useful synthons for bioactive natural products. These procedures address an important issue in diversity-oriented synthesis.