876392-17-5

Usage

Molecular structure

1H-Indole-2-butanal, 2,3-dihydro-3-methylene-1-[(4-methylphenyl)sulfonyl]is a complex organic compound with an indole core and additional functional groups.

Derivative of indole

The compound is derived from indole, a common structure found in natural products and pharmaceuticals.

Presence of sulfonyl group

The compound contains a sulfonyl group (-SO2-) which can be used as a reagent in organic synthesis and medicinal chemistry.

Presence of methylene group

The structure includes a methylene group (-CH2-) which can also be used in organic synthesis.

Biological activity potential

The compound's structure suggests potential for biological activity, making it a valuable target for further research and development.

Potential applications

Further exploration of its properties may lead to the discovery of new drugs, agrochemicals, or materials with unique properties.

Upstream product

• 62592-80-7 methyl trans-5-hydroxy-2-pentenoate 
• 30765-95-8 N-p-toluenesulfonyl-2-vinylaniline 
• 876392-11-9 N-(4-(methoxycarbonyl)-3-butenyl)-N-(p-toluenesulfonyl)-2-ethenylaniline 
• 894810-73-2 N-(4-(methoxycarbonyl)-1-butenyl)-N-(p-toluenesulfonyl)-2-ethenylaniline 
• 876392-15-3 N-(p-toluenesulfonyl)-2-(3-(methoxycarbonyl)propyl)-3-methylene-2,3-dihydroindole 

Downstream Products

• 876392-26-6 methanesulfonic acid 1-{3-[3-methylene-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-indol-2-yl]-propyl}-pentadecyl ester 
• 876392-07-3 N-(p-toluenesulfonyl)-2-octadecyl-3-methylene-2,3-dihydroindole 
• 876392-19-7 N-(p-toluenesulfonyl)-2-octadecyl-3-indolinone 
• 876392-24-4 1-[3-methylene-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-indol-2-yl]-octadecan-4-ol 

Relevant academic research and scientific papers

Development of isomerization and cycloisomerization with use of a ruthenium hydride with N-heterocyclic carbene and its application to the synthesis of heterocycles

A pure ruthenium hydride complex with N-heterocyclic carbene (NHC) ligand was efficiently generated from the reaction of a second-generation Grubbs ruthenium catalyst with vinyloxytrimethylsilane and unambiguously characterized. This ruthenium hydride complex showed high catalytic activity for the selective isomerization of terminal olefin and for the cycloisomerization of 1,6-dienes. These reactions of N-allyl-o-vinylaniline lead to novel synthetic methods for heterocycles such as indoles and 3-methylene-2,3-dihydroindoles, which are useful synthons for bioactive natural products. These procedures address an important issue in diversity-oriented synthesis.

Synthesis of the putative structure of fistulosin using the ruthenium-catalyzed cycloisomerization of diene

Fistulosin 1, which was isolated from the root of the Welsh onion, is a novel indole alkaloid that has antifungal activity. The first total synthesis of the reported structure of fistulosin using our cycloisomerization of diene is described.