876392-15-3 Usage
Molecular weight
429.57 g/mol This is the mass of a single molecule of Saquinavir, measured in grams per mole.
Appearance
White to off-white solid This describes the physical appearance of Saquinavir, which is a white to off-white solid substance.
Solubility
Practically insoluble in water, soluble in methanol and ethanol This indicates the solubility of Saquinavir in different solvents, which can affect how it is administered and absorbed in the body.
Mechanism of action
Protease inhibitor This describes how Saquinavir works to treat HIV/AIDS, by inhibiting the activity of the HIV protease enzyme, which is necessary for the replication of the virus.
Side effects
Diarrhea, nausea, changes in body fat distribution These are some of the potential side effects that may be experienced by individuals taking Saquinavir as part of their antiretroviral therapy.
Dosage form
Oral capsules This indicates the form in which Saquinavir is typically administered, as capsules taken by mouth.
Check Digit Verification of cas no
The CAS Registry Mumber 876392-15-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,6,3,9 and 2 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 876392-15:
(8*8)+(7*7)+(6*6)+(5*3)+(4*9)+(3*2)+(2*1)+(1*5)=213
213 % 10 = 3
So 876392-15-3 is a valid CAS Registry Number.
876392-15-3Relevant academic research and scientific papers
Development of isomerization and cycloisomerization with use of a ruthenium hydride with N-heterocyclic carbene and its application to the synthesis of heterocycles
Arisawa, Mitsuhiro,Terada, Yukiyoshi,Takahashi, Kazuyuki,Nakagawa, Masako,Nishida, Atsushi
, p. 4255 - 4261 (2007/10/03)
A pure ruthenium hydride complex with N-heterocyclic carbene (NHC) ligand was efficiently generated from the reaction of a second-generation Grubbs ruthenium catalyst with vinyloxytrimethylsilane and unambiguously characterized. This ruthenium hydride complex showed high catalytic activity for the selective isomerization of terminal olefin and for the cycloisomerization of 1,6-dienes. These reactions of N-allyl-o-vinylaniline lead to novel synthetic methods for heterocycles such as indoles and 3-methylene-2,3-dihydroindoles, which are useful synthons for bioactive natural products. These procedures address an important issue in diversity-oriented synthesis.
Synthesis of the putative structure of fistulosin using the ruthenium-catalyzed cycloisomerization of diene
Terada, Yukiyoshi,Arisawa, Mitsuhiro,Nishida, Atsushi
, p. 1269 - 1272 (2007/10/03)
Fistulosin 1, which was isolated from the root of the Welsh onion, is a novel indole alkaloid that has antifungal activity. The first total synthesis of the reported structure of fistulosin using our cycloisomerization of diene is described.
