87657-77-0 Usage
Molecular Weight
318.42 g/mol
Functional Groups
Hydroxyl (-OH), Methoxy (-OCH3), Phenyl (C6H5), and Heptanol (C7 alcohol)
Chemical Class
Phenolic compound, Alcohol
Structure
7-phenyl-3-heptanol backbone with a 4-hydroxy-3-methoxyphenyl substituent
Applications
Pharmaceutical industry, chemical research, drug development, and potential biological activities
Solubility
Likely soluble in organic solvents such as ethanol, methanol, and acetone due to its hydroxyl and methoxy functional groups
Boiling Point
Not directly provided, but expected to be relatively high due to its large molecular size and multiple aromatic rings
Melting Point
Not directly provided, but expected to be low to moderate due to the presence of a flexible heptanol chain and potential for intramolecular hydrogen bonding
Density
Not directly provided, but expected to be less than water due to its non-polar nature and large molecular size
Optical Properties
Not directly provided, but may exhibit some degree of UV-Vis absorption due to the presence of aromatic rings and conjugated systems
Stability
Likely stable under normal conditions, but sensitive to strong acids, bases, or oxidizing agents due to the presence of a phenolic hydroxyl group
Reactivity
May undergo reactions such as esterification, etherification, or oxidation due to the presence of hydroxyl and methoxy functional groups
Toxicity
Not directly provided, but should be handled with care and proper safety measures due to its complex structure and potential biological activities
Environmental Impact
Not directly provided, but potential environmental impact should be considered, especially if used in large quantities or released into the environment due to its complex structure and potential for persistence and bioaccumulation.
Check Digit Verification of cas no
The CAS Registry Mumber 87657-77-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,6,5 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 87657-77:
(7*8)+(6*7)+(5*6)+(4*5)+(3*7)+(2*7)+(1*7)=190
190 % 10 = 0
So 87657-77-0 is a valid CAS Registry Number.
87657-77-0Relevant academic research and scientific papers
Concise and efficient total synthesis of oxyphyllacinol, yakuchione-A and yakuchione-B
Shi, Xiang,Deng, Yu,Kurtz, Nicole C.,Sun, Yue,Xue, Mingxing,Wu, Xian
, p. 513 - 520 (2022/02/14)
A concise and efficient method for the large-scale total synthesis of oxyphyllacinol (1) has been achieved in six steps with an overall yield of 46%. Simultaneously, yakuchione-A (11) was obtained in a satisfactory yield (52%) during the process. By employing a Weinreb amide (6) as the key masonry block, yakuchione-B (13) was also constructed in a great overall yield (56%) and high purity. To overcome the challenges regarding the practical scale, high purity, and reproducibility, the synthetic route that was processed takes advantage of available materials, conventional reactions, and convenient purification methods without using column chromatography.
Synthesis of diarylheptanoids and assessment of their pungency
Itokawa,Aiyama,Ikuta
, p. 2491 - 2496 (2007/10/02)
With the aim of correlating pungency with substituent groups on one benzene ring, various analogues of yakuchinones were synthesized by means of the Claisen-Schmidt reaction. Their pungencies were assessed by direct comparison of the threshold concentrations obtained in taste experiments. The presence of a phenolic hydroxyl group was indispensable for high pungency, while that of a 1,2-double bond of the heptanone part tended to decrease the pungency.
