876953-21-8

Basic information

• Product Name: 3-Hexen-2-one, 5-methyl-4-phenyl-, (3E)-
• CAS NO: 876953-21-8
• Molecular Formula: C13H16O
• Molecular Weight: 188.269
• Mol File: 876953-21-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-Hexen-2-one, 5-methyl-4-phenyl-, (3E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hexen-2-one, 5-methyl-4-phenyl-, (3E)-(876953-21-8)
• EPA Substance Registry System: 3-Hexen-2-one, 5-methyl-4-phenyl-, (3E)-(876953-21-8)

Safety Data

• Hazardous Substances Data: 876953-21-8(Hazardous Substances Data)

Upstream product

• 611-70-1 phenyl isopropyl ketone 
• 62751-30-8 (E)-ethyl 4-methyl-3-phenylpent-2-enoate 
• 914400-07-0 (E)-N-methoxy-N,4-dimethyl-3-phenylpent-2-enamide 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 858932-57-7 (E,S)-5-methyl-4-phenyl-3-hexen-2-ol 
• 435269-66-2 (S)-5-methyl-4-phenylhexan-2-one 
• 162239-77-2 (R)-5-methyl-4-phenyl-hexan-2-one 
• 120609-18-9 (+/-)-5-methyl-4-phenylhexan-2-one 

Relevant articles and documents

The synthesis of non-racemic β-alkyl-β-aryl-disubstituted allyl alcohols and their transformation into allylamines and amino acids bearing a quaternary stereocenter

A synthesis of non-racemic β-alkyl-β-aryl allyl alcohols and their transformation into allylamines bearing a quaternary stereogenic center is reported. The allyl alcohols were prepared either by Cu-catalyzed enantioselective reduction of enones or by sequ

Asymmetric conjugate reduction of α,β-unsaturated ketones and esters with chiral rhodium(2,6-bisoxazolinylphenyl) catalysts

New asymmetric conjugate reduction of β,β-disubstituted α,β-unsaturated ketones and esters was accomplished with alkoxylhydrosilanes in the presence of chiral rhodium(2,6-bisoxazolinylphenyl) complexes in high yields and high enantioselectivity. (E)-4-Phenyl-3-penten-2- one and (E)-4-phenyl-4-isopropyl-3-penten-2-one were readily reduced at 60°C in 95% ee and 98 % ee, respectively, by 1 mol % of catalyst loading. (EtO) 2MeSiH proved to be the best hydrogen donor of choice. tert-Butyl (E)-β-methylcinnamate and β-isopropylcinnamate could also be reduced to the corresponding dihydrocinnamate derivatives up to 98% ee.