877-48-5

Basic information

• Product Name: 2,5-DIMETHYLPHENYL ACETATE
• Synonyms: 2,5-DIMETHYLPHENYL ACETATE;ACETIC ACID 2,5-DIMETHYL-PHENYL ESTER;2,5-xylyl acetate;2,5-Dimethylphenol acetate;(2,5-dimethylphenyl) ethanoate
• CAS NO: 877-48-5
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2
• EINECS: 212-893-6
• Mol File: 877-48-5.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 237°C (estimate)
• Flash Point: 88.8°C
• Appearance: /
• Density: 1.0624
• Vapor Pressure: 0.0891mmHg at 25°C
• Refractive Index: 1.5070 (estimate)
• CAS DataBase Reference: 2,5-DIMETHYLPHENYL ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DIMETHYLPHENYL ACETATE(877-48-5)
• EPA Substance Registry System: 2,5-DIMETHYLPHENYL ACETATE(877-48-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 877-48-5(Hazardous Substances Data)

Usage

General Description

2,5-DIMETHYLPHENYL ACETATE is a chemical compound with the molecular formula C10H12O2. It belongs to the class of organic compounds known as phenyl acetates, which are compounds containing an acetate group conjugated to a phenyl group. This chemical is commonly used as a fragrance and flavoring agent in various consumer products, including perfumes, colognes, and food and beverage products. It has a sweet, floral, and fruity aroma, making it a popular choice for adding a pleasant scent to a wide range of products. Additionally, 2,5-DIMETHYLPHENYL ACETATE is also used in the synthesis of other organic compounds and has been studied for its potential pharmaceutical applications.

InChI:InChI=1/C10H12O2/c1-7-4-5-8(2)10(6-7)12-9(3)11/h4-6H,1-3H3

Upstream product

• 54874-32-7 (E)-1,4-dimethyl-4-nitrocyclohexa-2,5-dienyl acetate 
• 54874-31-6 1,4-dimethyl-c-4-nitrocyclohexa-2,5-dien-r-1-yl acetate 
• 106-42-3 para-xylene 
• 108-24-7 acetic anhydride 
• 95-87-4 2,5-Dimethylphenol 
• 75-36-5 acetyl chloride 
• 64-19-7 acetic acid 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 10534-59-5 tetrabutylammonium acetate 
• 132907-18-7 3,6-dimethoxy-3,6-dimethylcyclohexa-1,4-diene 
• 127-08-2 potassium acetate 

Downstream Products

• 125672-79-9 2,5-bis(bromomethyl)phenyl acetate 
• 26216-10-4 1-(4-hydroxy-2,5-dimethylphenyl)ethanone 
• 853562-08-0 4-(2-bromoethyl)-2,5-dimethylphenol 
• 107584-78-1 2-bromo-1-(4-hydroxy-2,5-dimethylphenyl)ethanone 
• 853562-09-1 4-(2-azidoethyl)-2,5-dimethylphenol 
• 853562-11-5 [2-(4-hydroxy-2,5-dimethylphenyl)ethyl]carbamic acid tert-butyl ester 
• 853562-12-6 [2-(4-hydroxy-3-iodo-2,5-dimethylphenyl)ethyl]carbamic acid tert-butyl ester 
• 853562-02-4 3-[3-(2-tert-butoxycarbonylaminoethyl)-6-hydroxy-2,5-dimethylphenyl]propionic acid methyl ester 
• 853562-13-7 3-[3-(2-tert-butoxycarbonylaminoethyl)-6-hydroxy-2,5-dimethylphenyl]acrylic acid methyl ester 
• 6245-04-1 3,5-dimethylsalicylic acid 
• 1198-66-9 3,5-dimethyl-2-hydroxyacetophenone 
• 95-87-4 2,5-Dimethylphenol 
• 90743-02-5 2-hydroxy-3,6-dimethylacetophenone 

Relevant articles and documents

Direct Acetoxylation of Arenes

Acetoxylation of arenes is an important reaction and an unmet need in chemistry. We report a metal-free, direct acetoxylation reaction using sodium nitrate under an anhydrous environment of trifluoroacetic acid, acetic acid, and acetic anhydride. Arenes (31 examples), with oxidation potentials (Eox, in V vs SCE) lower than benzene (2.48 V), were acetoxylated with good yields and regioselectivity. A stepwise, single electron-transfer mechanism is proposed.

Reusable and efficient polyvinylpolypyrrolidone-supported triflic acid catalyst for acylation of alcohols, phenols, amines, and thiols under solvent-free conditions

Abstract: A triflic acid-functionalized polyvinylpolypyrrolidone was prepared and fully characterized by FT-IR, TGA, and SEM. This super acidic solid catalyst shows high catalytic activity for selective acylation of alcohols, phenols, amines, and thiols with anhydrides under solvent-free conditions at room temperature. In addition, this method features an easy to handle solid super acid catalyst and an operationally simple procedure, affording the desired acylated products in excellent yields. Graphical abstract: [Figure not available: see fulltext.].

Palladium-catalyzed annulation of 2,2′-diiodobiphenyls with alkynes: Synthesis and applications of phenanthrenes

A range of phenanthrene derivatives were efficiently synthesized by the palladium-catalyzed annulation of 2,2′-diiodobiphenyls with alkynes. The scope, limitations and regioselectivity of the reaction were investigated. The described method was adopted to synthesize 9,10-dialkylphenanthrenes, sterically overcrowded 4,5-disubstituted phenanthrenes and phenanthrene-based alkaloids. Reactions of highly methoxy-substituted biphenyls with 2-(2-propynyl)pyrrolidine and 2-(2-propynyl)piperidine gave 2-(9-phenanthylmethyl)pyrrolidines and 2-(9-phenanthylmethyl)piperidines, respectively. The products were transformed to phenanthroindolizidine and phenanthroquinolizidine alkaloids by the Pictet-Spengler reaction.