877-82-7Relevant articles and documents
An efficient method to prepare aryl acetates by the carbonylation of aryl methyl ethers or phenols
Zhang, Dejin,Yang, Guoqiang,Xiong, Junping,Liu, Jia,Hu, Xingbang,Zhang, Zhibing
, p. 2683 - 2687 (2021/02/16)
Synthesis of valuable chemicals from lignin based compounds is critical for the application of biomass. Here, we develop a method of preparing aryl acetates by the carbonylation of aryl methyl ethers or phenols under low CO pressure. Good to excellent yields of aryl acetates were obtained using different substrates, and a possible reaction mechanism was proposed by conducting a series of control experiments. This method may provide a potential way for the utilization of lignin.
Inhibiting Aβ toxicity in Alzheimer's disease by a pyridine amine derivative
Zhu, Zhenzhu,Yang, Tao,Zhang, Lei,Liu, Lulu,Yin, Enmao,Zhang, Changli,Guo, Zijian,Xu, Chen,Wang, Xiaoyong
, p. 330 - 339 (2019/03/02)
Alzheimer's disease (AD) is a neurodegenerative disorder with no radical therapy. Aggregation of amyloid β-peptide (Aβ) induced by various factors is associated with pathogenesis of AD. A pyridine amine derivative, 3-bis(pyridin-2-ylmethyl)aminomethyl-5-h
Synthesis of dansyl labeled sphingosine kinase 1 inhibitor
Park, Eun-Young,Lee, Taeho,Oh, Yoon Sin,Lee, Joo-Youn,Shrestha, Jitendra,Hong, Seung Woo,Jin, Yun Ji,Jo, GeunHyung,Kim, Sanghee,Hwang, Gil Tae,Han, Dong-Sul,Baek, Dong Jae
, p. 29 - 33 (2018/07/31)
PF-543 is a non-sphingosine analogue with inhibitory effect against SK1, based on a Ki of 4.3 nM and 130-fold selectivity for SK1 over SK2. Since the development of PF-543, animal studies demonstrated its valuable role in multiple sclerosis, myocardial in
