87717-18-8

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 24942-76-5 1-chloro-2-styrylbenzene 
• 100-42-5 styrene 
• 6091-64-1 2-bromobenzoic acid ethyl ester 
• 6163-58-2 tris-(o-tolyl)phosphine 
• 617-86-7 triethylsilane 
• 110166-71-7 ethyl 2-(phenylethynyl)benzoate 

Downstream Products

• 5505-02-2 ethyl 2-phenethylbenzoate 
• 60901-21-5 o-styrylbenzoic acid 
• 4890-85-1 o-phenethylbenzoic acid 
• 75250-37-2 3,4-dihydro-3-phenyl-4-(phenylseleno)isocoumarin 
• 63404-82-0 (E)-2-styrylbenzamide 
• 204847-93-8 trans-stilbene-2-carbonyl chloride 
• 4809-08-9 3-phenyl-isocoumarin 
• 7115-13-1 3-phenyl-2H-isoquinolin-1-one 

Relevant academic research and scientific papers

Aryllithiums with increasing steric crowding and lipophilicity prepared from chlorides in diethyl ether. the first directly prepared room-temperature-stable dilithioarenes

A convenient procedure has been developed for the preparation of synthetically useful, room-temperature-stable aryllithiums starting from aryl chlorides and lithium metal. The method provides a route to aryllithiums which have previously not been accessible cleanly or could only be prepared by using more expensive starting materials.

Platinum oxide catalyzed hydrosilylation of unsymmetrical internal aryl alkynes under ortho-substituent regiocontrol

(Chemical Equation Presented) PtO2- and H2PtCl 6-catalyzed hydrosilylation of internal aryl alkynes having a para or an ortho substituent with triethylsilane are discussed and compared. The regioselectivity of the H-Si bond addition was found to be controlled by the ortho substituent rather than the nature of the platinum catalyst. Arylalkynes with an ortho substituent, regardless of its electronic nature, directed the silyl substituent mainly to the α-position. PtO2 proved to be a versatile and powerful catalyst compared to H2PtCl6 since it prevents the alkyne reduction.

Benzamidoaldehydes and their use as cysteine protease inhibitors

Compounds of the formula where R1, R2, R3, X and n are as defined in the description, are inhibitors of cysteine protease.

Synthesis of Isocoumarin, 1-Isoquinolone and 4(1H)-Quinolone Derivatives via Seleno-intermediates

The reaction of 2-styrylbenzoic acid 2 with N-phenylselenosuccinimide (N-PPS) affords 3-phenyl-iso-coumarin derivatives 3 and 3,4-dihydro-3-phenyl-4-(phenylseleno)isocoumarins 4 via selenolactonization.The reaction of 2-styrylbenzamides 5 and 1-(2-aminoph