63404-82-0Relevant academic research and scientific papers
The rhodium-catalyzed selective oxidative Heck reaction of amides with allylic esters
Hei, Yu-Yuan,Song, Jian-Lan,Zhan, Xin-Chen,Zhang, Xing-Guo,Deng, Chen-Liang
, p. 1557 - 1561 (2019)
The Rh-catalyzed direct selective oxidation Heck reaction of benzamides with allylic esters has been developed for the synthesis of amides and isoquinolin-1-ones. According to the functional groups on N-atom, benzamides or isoquinolin-1-ones were synthesi
Ru(II)-Catalyzed Controlled Cross-Dehydrogenative Coupling of Benzamides with Activated Olefins via Weakly Coordinating Primary Amides
Baghel, Akanksha Singh,Aghi, Anjali,Kumar, Amit
, p. 9744 - 9754 (2021/07/26)
Ru(II)-catalyzed regioselective ortho-alkenylation of primary benzamides with activated olefins has been realized over the competitive cyclized products. This reaction overall proceeds via a cross-dehydrogenative coupling (CDC) reaction using a simple and
Rhodium-Catalyzed Electrooxidative C?H Olefination of Benzamides
Ackermann, Lutz,Struwe, Julia,Zhang, Yan
supporting information, p. 15076 - 15080 (2020/06/20)
Metal-catalyzed chelation-assisted C?H olefinations have emerged as powerful tools for the construction of functionalized alkenes. Herein, we describe the rhoda-electrocatalyzed C?H activation/alkenylation of arenes. The olefinations of challenging electron-poor benzamides were thus accomplished in a fully dehydrogenative fashion under electrochemical conditions, avoiding stoichiometric chemical oxidants, and with H2 as the only byproduct. This versatile alkenylation reaction also features broad substrate scope and used electricity as a green oxidant.
Aerobic Oxidative Olefination of Benzamides with Styrenes Catalyzed by a Moderately Electron-Deficient CpRh(III) Complex with a Pendant Amide
Yoshimura, Ryo,Shibata, Yu,Yamada, Takayuki,Tanaka, Ken
, p. 2501 - 2511 (2019/03/08)
It has been established that a newly developed moderately electron-deficient cyclopentadienyl (Cp)-Rh(III) complex, bearing ester and pendant amide moieties on the Cp ring [CpARh(III)], is able to catalyze the aerobic oxidative olefination of b
Intramolecular Hydroamidation of ortho-Vinyl Benzamides Promoted by Potassium tert-Butoxide/N,N-Dimethylformamide
Chen, Zhen-Yu,Wu, Liang-Yu,Fang, Hai-Sheng,Zhang, Ting,Mao, Zhi-Feng,Zou, Yong,Zhang, Xue-Jing,Yan, Ming
supporting information, p. 3894 - 3899 (2017/10/07)
An intramolecular hydroamidation of ortho-vinyl benzamides had been developed. The reaction was promoted efficiently by potassium tert-butoxide and N,N-dimethylformamide without the need for strong oxidants or transition-metal catalysts. A series of dihyd
Rh(III)-catalyzed Directed C-H Olefination using an oxidizing directing group: Mild, efficient, and versatile
Rakshit, Souvik,Grohmann, Christoph,Besset, Tatiana,Glorius, Frank
, p. 2350 - 2353 (2011/05/04)
An efficient Rh(III)-catalyzed oxidative olefination by directed C-H bond activation of N-methoxybenzamides is reported. In this mild, practical, selective, and high-yielding process, the N-O bond acts as an internal oxidant. In addition, simply changing the substituent of the directing/oxidizing group results in the selective formation of valuable tetrahydroisoquinolinone products.
Rhodium-catalyzed oxidative olefination of C-H Bonds in Acetophenones and Benzamides
Patureau, Frederic W.,Besset, Tatiana,Glorius, Frank
supporting information; experimental part, p. 1064 - 1067 (2011/04/16)
A good neighborhood! The metal-catalyzed oxidative C-H functionalization of electron-rich arenes is well-established, but analogous reactions of electron-poor substrates are rare. A new application makes use of common electron-withdrawing functional groups (COMe, CONH2, CONEt 2) in the rhodium-catalyzed oxidative Heck reaction to generate complex organic molecules. Cp= I·5-C5Me 5.
Synthesis of Isocoumarin, 1-Isoquinolone and 4(1H)-Quinolone Derivatives via Seleno-intermediates
Izumi, Taeko,Morishita, Nobuya
, p. 145 - 152 (2007/10/02)
The reaction of 2-styrylbenzoic acid 2 with N-phenylselenosuccinimide (N-PPS) affords 3-phenyl-iso-coumarin derivatives 3 and 3,4-dihydro-3-phenyl-4-(phenylseleno)isocoumarins 4 via selenolactonization.The reaction of 2-styrylbenzamides 5 and 1-(2-aminoph
