877373-78-9

Upstream product

• 159593-22-3 diethyl (2S,3S)-2,3-di-O-methoxymethyl-tartrate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 166734-76-5 (2R,3R)-2,3-bis(methoxymethoxy)butane-1,4-diol 

Downstream Products

• 1616247-12-1 (2R,3R,4S)-8-azido-1-(tert-butyldiphenylsilyloxy)-2,3-bis(methoxymethoxy)octan-4-ol 
• 1616247-11-0 (5S,6R,7R)-8-(tert-butyldiphenylsilyloxy)-6,7-bis(methoxymethoxy)octane-1,5-diol 
• 1616247-09-6 (2R,3R,4S)-1-(tert-butyldiphenylsilyloxy)-2,3-bis(methoxymethoxy)oct-7-en-4-ol 
• 1616247-10-9 (2R,3R,4R)-1-(tert-butyldiphenylsilyloxy)-2,3-bis(methoxymethoxy)oct-7-en-4-ol 
• 925222-04-4 (4S,5S,6R)-5-benzyloxy-3,3-dimethyl-7-[(1,1-dimethylethyl)diphenylsilyl]oxy-4-methoxy-6-(trimethylsilyl)oxy-1-heptene 
• 925222-06-6 (2R,3R,4S,6R)-6-(bromomethyl)-2-[(tert-butyldiphenylsilyloxy)methyl]-4-methoxy-5,5-dimethyltetrahydro-2H-pyran-3-yl benzoate 
• 925222-05-5 (4S,5S,6R)-5-benzyloxy-3,3-dimethyl-7-[(1,1-dimethylethyl)diphenylsilyl]oxy-4-methoxy-6-hydroxy-1-heptene 
• 925222-03-3 (4S,5S,6R)-3,3-dimethyl-7-[(1,1-dimethylethyl)diphenylsilyl]oxy-5-hydroxy-4-methoxy-6-(trimethylsilyl)oxy-1-heptene 
• 925222-01-1 [(R)-2-((2R,3S)-5-Bromomethyl-3-methoxy-4,4-dimethyl-tetrahydro-furan-2-yl)-2-methoxymethoxy-ethoxy]-tert-butyl-diphenyl-silane 
• 925222-13-5 (4S,5S,6R)-3,3-dimethyl-7-[(1,1-dimethylethyl)diphenylsilyl]oxy-4,5-O-isopropylidene-6-hydroxy-1-heptene 
• 855282-51-8 tert-Butyl-((2R,3R,4S)-4-methoxy-2,3-bis-methoxymethoxy-5,5-dimethyl-hept-6-enyloxy)-diphenyl-silane 
• 855282-04-1 (4S,5R,6R)-5,6-bis(methoxymethoxy)-3,3-dimethyl-7-[(1,1-dimethylethyl)diphenylsilyl]oxy-4-hydroxy-1-heptene 
• 855282-22-3 (4S,5S,6R)-5,6-dihydroxy-3,3-dimethyl-7-[(1,1-dimethylethyl)diphenylsilyl]oxy-4-methoxy-1-heptene 
• 877373-38-1 (2S,3R)-2,3-bis(methoxymethoxy)-4-[(1,1-dimethylethyl)diphenylsilyl]oxybutyraldehyde 

Relevant academic research and scientific papers

Studies toward the asymmetric synthesis of the right part of the mycalamides

Described herein is the asymmetric synthesis of a functionalized, trioxadecalin unit that comprises the right-hand part of the mycalamides and related natural products. The synthetic route involves a 16-step sequence that accomplishes the formation of two