925222-03-3

Upstream product

• 877373-78-9 (2R,3R)-4-(tert-Butyl-diphenyl-silanyloxy)-2,3-bis-methoxymethoxy-butan-1-ol 
• 877373-38-1 (2S,3R)-2,3-bis(methoxymethoxy)-4-[(1,1-dimethylethyl)diphenylsilyl]oxybutyraldehyde 
• 855282-51-8 tert-Butyl-((2R,3R,4S)-4-methoxy-2,3-bis-methoxymethoxy-5,5-dimethyl-hept-6-enyloxy)-diphenyl-silane 
• 855282-04-1 (4S,5R,6R)-5,6-bis(methoxymethoxy)-3,3-dimethyl-7-[(1,1-dimethylethyl)diphenylsilyl]oxy-4-hydroxy-1-heptene 
• 855282-22-3 (4S,5S,6R)-5,6-dihydroxy-3,3-dimethyl-7-[(1,1-dimethylethyl)diphenylsilyl]oxy-4-methoxy-1-heptene 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 925222-04-4 (4S,5S,6R)-5-benzyloxy-3,3-dimethyl-7-[(1,1-dimethylethyl)diphenylsilyl]oxy-4-methoxy-6-(trimethylsilyl)oxy-1-heptene 
• 925222-06-6 (2R,3R,4S,6R)-6-(bromomethyl)-2-[(tert-butyldiphenylsilyloxy)methyl]-4-methoxy-5,5-dimethyltetrahydro-2H-pyran-3-yl benzoate 
• 925222-05-5 (4S,5S,6R)-5-benzyloxy-3,3-dimethyl-7-[(1,1-dimethylethyl)diphenylsilyl]oxy-4-methoxy-6-hydroxy-1-heptene 
• 925222-17-9 (4S,5S,6R)-6-benzyloxy-3,3-dimethyl-5,7-O-isopropylidene-4-methoxy-1-heptene 
• 1054641-55-2 (4S,5S,6R)-6-benzyloxy-5,7-dihydroxy-3,3-dimethyl-4-methoxy-1-heptene 

Relevant academic research and scientific papers

Studies toward the asymmetric synthesis of the right part of the mycalamides

Described herein is the asymmetric synthesis of a functionalized, trioxadecalin unit that comprises the right-hand part of the mycalamides and related natural products. The synthetic route involves a 16-step sequence that accomplishes the formation of two