877642-99-4Relevant academic research and scientific papers
Synthesis and evaluation of anti-HSV activity of new 5-alkynyl-2′- deoxyuridines
Pchelintseva,Skorobogatyj,Petrunina,Andronova,Galegov,Astakhova,Ustinov,Malakhov,Korshun, Vladimir A.
, p. 923 - 926 (2005)
Eight 5-alkynyl-2′deoxyuridines containing different bulky substituents have been prepared and tested against HSV-1 in Vero cells. The compounds show positive antiviral activity. There is no obvious correlation between activity and substituent size. The n
5-Alkynyl-2′-deoxyuridines, containing bulky aryl groups: Evaluation of structure-anti-HSV-1 activity relationship
Skorobogatyi, Mikhail V.,Pchelintseva, Anna A.,Petrunina, Anna L.,Stepanova, Irina A.,Andronova, Valeriya L.,Galegov, Georgi A.,Malakhov, Andrei D.,Korshun, Vladimir A.
, p. 1279 - 1287 (2007/10/03)
Four 5-alkynyl-2′-deoxyuridines containing different bulky substituents and flexible linkers between the triple bond and the aromatic residue have been prepared and tested against HSV-1 in Vero cells. Two nucleosides containing carbonyl groups, 5-(4-benzo
