Synthesis and evaluation of anti-HSV activity of new 5-alkynyl-2′- deoxyuridines

DOI: 10.1081/NCN-200059280

Source and publish data:

Nucleosides, nucleotides and nucleic acids p. 923 - 926 (2005)

Update date:2022-08-10

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Authors:

Pchelintseva

Skorobogatyj

Petrunina

Andronova

Galegov Galegov

Astakhova

Ustinov Ustinov

Malakhov

Korshun, Vladimir A.

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Article abstract of DOI:10.1081/NCN-200059280

Eight 5-alkynyl-2′deoxyuridines containing different bulky substituents have been prepared and tested against HSV-1 in Vero cells. The compounds show positive antiviral activity. There is no obvious correlation between activity and substituent size. The n

Full text of DOI:10.1081/NCN-200059280

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