877814-98-7Relevant academic research and scientific papers
Substituted 4-hydroxyphenyl sulfonamides as pathway-selective estrogen receptor ligands
Sabatucci, Joseph P.,Ashwell, Mark A.,Trybulski, Eugene,O'Donnell, Mary-Margaret,Moore, William J.,Harnish, Douglas C.,Chadwick, Christopher C.
, p. 854 - 858 (2006)
The transcription factor nuclear factor-κB (NF-κB) is a key component in the onset of inflammation. We describe here a series of 4-hydroxyphenyl sulfonamide estrogen receptor (ER) ligands that selectively inhibit NK-κB transcriptional activity but are devoid of conventional estrogenic activity.
AMINE COMPOUND FOR INHIBITING SSAO / VAP-1 AND USE THEREOF
-
Paragraph 0282; 0287; 0553-0555, (2020/12/13)
An amine compound serving as a semicarbazide-sensitive amine oxidase (SSAO) and/or vascular adhesion protein-1 (VAP-1) inhibitor, a pharmaceutical composition, and an application thereof in medicines that can be used for treating inflammation and/or inflammation related diseases, diabetes and/or a disease related diabetes, psychiatric disorder, ischemic disease, vascular disease, fibrosis, or tissue transplant rejection.
