878293-48-2

Upstream product

• 369365-14-0 dimethyl (2S,3R)-3-methyl-2-O-tosylmalate 
• 50460-80-5 (2S)-2-Hydroxy-3-methyl-bernsteinsaeuredimethylester 
• 99328-41-3 (2R,3S)-3-(tert-butyldimethylsilyloxy)-2-methylbutanal 
• 108763-90-2 (2S,3S)-3-((1,1-dimethylethyl)dimethylsiloxy)-2-methyl-1-butanol 
• 116782-41-3 (2S,3S)-2-methylbutane-1,3-diol 
• 878293-46-0 (2S,3S)-1,3-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methyl-butane 
• 878293-47-1 (E)-(4S,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-hex-2-enoic acid ethyl ester 
• 149400-42-0 ethyl (2E,4E)-4-methylhexa-2,4-dienoate 
• 497-03-0 2-methylbut-2-enal 
• 914366-83-9 (E)-ethyl 3-((4S,5S)-4,5-dimethyl-2-oxo-1,3-dioxolan-4-yl)acrylate 
• 914366-76-0 (E,4S,5S)-ethyl 4,5-dihydroxy-4-methylhex-2-enoate 
• 878293-45-9 (E,4S,5S)-ethyl 5-hydroxy-4-methylhex-2-enoate 
• 100-52-7 benzaldehyde 

Relevant academic research and scientific papers

Total synthesis of 6-epiprelactone-V via a syn-selective oxygen tethered intramolecular Michael reaction

The intramolecular protective group (benzylidene acetal) assisted syn-1,3-diol synthesis has been efficiently utilized in a short synthesis of 6-epiprelactone-V starting from (S)-malic acid.

De novo synthesis of 2-substituted syn-1,3-diols via an iterative asymmetric hydration strategy

(Chemical Equation Presented) The enantioselective syntheses of several protected 4-substituted syn-3,5-dihydroxy carboxylic esters have been achieved from the corresponding achiral (E,E)- or (E,Z)-1,3-dienoates. The route relies upon an enantio- and regi