878757-08-5 Usage
General Description
The chemical (R)-(-)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propylamine, also known as "THANDRA", is a chiral amine compound with a complex molecular structure. It is a member of the amphetamine class of drugs and has been found to possess psychoactive and stimulating effects. THANDRA is a potent and selective dopamine and norepinephrine releasing agent, meaning it increases the levels of these neurotransmitters in the brain. It has been studied for its potential use as a treatment for attention-deficit hyperactivity disorder (ADHD) and also has potential as a recreational drug due to its stimulating effects. However, its use and distribution are strictly regulated due to its potential for abuse and addiction.
Check Digit Verification of cas no
The CAS Registry Mumber 878757-08-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,8,7,5 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 878757-08:
(8*8)+(7*7)+(6*8)+(5*7)+(4*5)+(3*7)+(2*0)+(1*8)=245
245 % 10 = 5
So 878757-08-5 is a valid CAS Registry Number.
878757-08-5Relevant articles and documents
An investigation on key parameters that influence the synthesis of (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propylamine: A key intermediate for duloxetine
Suthrapu, Sashikanth,Sripathi, Somaiah,Veeramalla, Raju,Bojja, Ramachandra Reddy,Karnati, Venugopal Reddy
, p. 854 - 856 (2009)
This document highlights the systematic study of influencing factors such as temperature, base, catalyst, and solvent volume in the synthesis of (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propylamine oxalate 11a, without affecting the chiral
A NOVEL PROCESS FOR THE PREPARATION OF (S)-(+)-N,N-DIMETHYL-3-(1-NAPHTHALENYLOXY)-3-(2-THIENYL)PROPANAMINE, A DULOXETINE INTERMEDIATE
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Page/Page column 6, (2010/11/28)
Provided is a process for preparing a duloxetine intermediate,(S)-(+)-N,N-Dimethyl-3-(1- naphthalenyloxy)-3-(2-thienyl)propanamine (DNT), and its conversion to duloxetine or a pharmaceutically acceptable salt thereof.
