87951-12-0

Basic information

• Product Name: 2-Propenoic acid, 3-(dimethylamino)-2-isocyano-, ethyl ester
• CAS NO: 87951-12-0
• Molecular Formula: C8H12N2O2
• Molecular Weight: 168.195
• Mol File: 87951-12-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(dimethylamino)-2-isocyano-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(dimethylamino)-2-isocyano-, ethyl ester(87951-12-0)
• EPA Substance Registry System: 2-Propenoic acid, 3-(dimethylamino)-2-isocyano-, ethyl ester(87951-12-0)

Safety Data

• Hazardous Substances Data: 87951-12-0(Hazardous Substances Data)

Upstream product

• 5815-08-7 tert-Butoxybis(dimethylamino)methane 
• 2999-46-4 Ethyl isocyanoacetate 

Downstream Products

• 1260793-84-7 1-isopropyl-1H-imidazole-4-carboxylic acid ethyl ester 
• 1448869-67-7 2-bromo-1-isopropyl-1H-imidazole-4-carboxylic acid ethyl ester 
• 1335139-23-5 C₁₈H₃₂N₂O₃Si 
• 1335139-47-3 ethyl 1-(cis-4-{[tert-butyl(diphenyl)silyl]oxy}cyclohexyl)-1H-imidazole-4-carboxylate 
• 1335139-13-3 C₁₄H₂₂N₂O₂ 
• 1335139-09-7 ethyl 1-(trans-4-methylcyclohexyl)-1H-imidazole-4-carboxylate 
• 1335139-39-3 ethyl 1-(3,3-dimethylcyclohexyl)-1H-imidazole-4-carboxylate 
• 1260655-20-6 C₁₄H₁₂ClF₃N₂O₂ 
• 1219036-45-9 C₂₃H₂₇N₅O₂S 
• 14527-43-6 ethyl thiazole-4-carboxylate 

Relevant articles and documents

Orthoamides, XXXII. - Reactions of tert-Butoxy-N,N,N',N'-tetramethylmethanediamine with NH- and CH-acidic Compounds

tert-Butoxy-N,N,N',N'-tetramethylmethanediamine (1) reacts with N-formylglycine ethyl ester (2) and with N-formyl-β-alanine ethyl ester (9) to form the aminomethylene compounds 3 and 10, respectively.Glycine ester is aminomethylenated by 1 at the acidic NH2 group to give the amidine 6.Dimethylaminoformaldehyde dimethyl acetal (5) is also suitable for this reaction.On reaction with 1 the compounds 3 as well as 6 yield the amidine 4.N-Monosubstituted formamides are transformed by 1 into formamidines 13.Reaction of isocyanoacetate 17 and 1 affords the enamine 18, whereas reaction of benzyl isonitrile with 1 gives the amidine 19. 2-Alkyl-Δ2-oxazolines 21, carboximidates 23, 25, and amidines 27 are aminomethylenated by 1 to yield the products 22, 24, 26, and 28, respectively.The vinylogous guanidinium salt 34 is obtained by reaction of 1 with N,N,N',N'-tetramethylacetamidinium tetrafluoroborate (31a).Phosphonates 36 react with 1 to afford the enamines 37.The reaction of 1 on ethyl trimethylsilylacetate (39) gives rise to formation of ethyl 3-dimethylaminoacrylate (11).