88039-67-2Relevant academic research and scientific papers
Necic Acid Synthons. Part 2. Regioselectivity in the Reactions of (Z)-2-Bromomethyl-2-alkenoate Esters with Selected Carbon Nucleophiles
Ameer, Farouk,Drewes, Siegfried E.,Emslie, Neville D.,Kaye, Perry T.,Mann, R. Leigh
, p. 2293 - 2295 (2007/10/02)
The preparation of selected (Z)-2-bromomethyl-2-alkenoate esters and their subsequent reaction with acetoacetic ester-derived nucleophiles is described.Both the substrate structure and the solvent system have significant effects on the regioselectivity of these nucleophilic displacements.
