880644-86-0

Upstream product

• 880644-82-6 N-[(R)-2-amino-3-(p-nitrophenyl)propyl]-trans-(S,S)-cyclohexane-1,2-diamine-N,N,N',N'',N''-penta-tert-butyl acetate 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 880644-84-8 N-[(R)-2-amino-3-(p-aminophenyl)propyl]-trans-(S,S)-cyclohexane-1,2-diamine-N,N,N',N'',N''-penta-tert-butyl acetate 
• 905825-53-8 N-[(R)-2-amino-3-(p-aminophenyl-N-{5-oxopentanoic acid})-propyl]-trans-(S,S)-cyclohexane-1,2-diamine-N,N,N',N'',N''-penta-tert-butyl acetate 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 

Relevant academic research and scientific papers

Validation of a novel CHX-A″ derivative suitable for peptide conjugation: Small animal PET/CT imaging using yttrium-86-CHX-A″- octreotide

A versatile bifunctional chelating reagent based on a preorganized cyclohexyl derivative of DTPA (CHX-A′) has been developed for the convenient N-terminal labeling of peptides with metal ion radionuclides of Bi(III), In(III), Lu(III), or Y(III). This was

METAL CHELATORS AND METHODS OF THEIR USE

Metal chelators of Formula (I) and Formula (II) are disclosed or a farmaceutically acceptable salt thereof. Also disclosed are metal chelator-targeting moiety complexes, metal chelator-targeting moiety-metal conjugates, kits, and methods of their preparation and use in diagnosis and/or treatment of diseases and conditions, including, inter alia, cancer and thrombosis.