880762-37-8

Basic information

• Product Name: L-Cysteine, N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-S-(triphenylmethyl)-
• CAS NO: 880762-37-8
• Molecular Formula: C30H25F4NO2S
• Molecular Weight: 539.594
• Mol File: 880762-37-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: L-Cysteine, N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-S-(triphenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Cysteine, N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-S-(triphenylmethyl)-(880762-37-8)
• EPA Substance Registry System: L-Cysteine, N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-S-(triphenylmethyl)-(880762-37-8)

Safety Data

• Hazardous Substances Data: 880762-37-8(Hazardous Substances Data)

Usage

General Description

L-Cysteine, N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-S-(triphenylmethyl)- is a chemical compound that combines the amino acid L-cysteine with a trifluoroethyl group and a triphenylmethyl group. The trifluoroethyl group contains a fluorophenyl ring, adding a fluorine atom to the compound. The triphenylmethyl group is a bulky protecting group that can be removed under specific conditions to unveil the reactive thiol group of the cysteine amino acid. L-Cysteine, N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-S-(triphenylmethyl)- may have various applications in organic chemistry, biochemistry, and pharmaceutical research due to its unique structure and reactivity.

Upstream product

• 17556-41-1 2,2,2-trifluoro-1-(4-fluorophenyl)ethanol 
• 655-32-3 2,2,2-trifluoro-1-(4-fluorophenyl)ethanone 
• 2799-07-7 S-trityl-L-cysteine 
• 880762-43-6 trifluoromethanesulfonic acid (R)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl ester 
• 2799-07-7 (S)-trityl-D-cysteine 
• 84877-46-3 2,2,2-trifluoro-1-phenylethyl trifluoromethanesulfonate 
• 848836-58-8 2,2,2-trifluoro-1-(4-fluorophenyl)ethyl trifluoromethanesulfonate 
• 25683-09-4 3-(triphenylmethylthio)-alanine 
• 890040-25-2 trifluoromethanesulfonic acid 2,2,2-trifluoro-1-(S)-phenylethyl ester 
• 84877-47-4 trifluoromethanesulfonic acid 2,2,2-trifluoro-1(R)-phenylethyl ester 

Downstream Products

• 1408001-10-4 2(R)-[2,2,2-trifluoro-1(R)-(4-fluorophenyl)ethylamino]-3-(cyclopropylmethanesulfanyl)propionic acid 
• 849094-18-4 (R)-3-((cyclopropylmethyl)thio)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)amino)propanoic acid 
• 890040-32-1 (R)-N-(1-cyanocyclopropyl)-2-[(S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino]-3-tritylsulfanyl-propionamide 
• 910866-66-9 3-mercapto-2(R)-[2,2,2-trifluoro-1(S)-(4-fluorophenyl)ethylamino]-propionic acid 
• 849094-17-3 2(R)-[2,2,2-trifluoro-1(RS)-(4-fluorophenyl)ethylamino]-3-cyclopropylmethanesulfanylpropionic acid 

Relevant articles and documents

SULFONYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

ALPHA KETOAMIDE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

SULFONAMIDE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS

The present invention is directed to compounds of formula ( I ) that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them. Wherein R3 is-alkylene-SO2NR5R6.