849094-18-4

Basic information

• Product Name: L-Cysteine, S-(cyclopropylmethyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-
• Synonyms: 2(R)-[2,2,2-trifluoro-1(S)-(4-fluorophenyl)ethylamino]-3-(cyclopropylmethanesulfanyl)propionic acid;2(R)-[2,2,2-trifluoro-1(RS)-(4-fluorophenyl)ethylamino]-3-cyclopropylmethanesulfanylpropionic acid
• CAS NO: 849094-18-4
• Molecular Formula: C15H17F4NO2S
• Molecular Weight: 351.36000
• Mol File: 849094-18-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Cysteine, S-(cyclopropylmethyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Cysteine, S-(cyclopropylmethyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-(849094-18-4)
• EPA Substance Registry System: L-Cysteine, S-(cyclopropylmethyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-(849094-18-4)

Safety Data

• Hazardous Substances Data: 849094-18-4(Hazardous Substances Data)

Usage

General Description

The chemical compound L-Cysteine, S-(cyclopropylmethyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]- is a derivative of the amino acid L-cysteine that contains a cyclopropylmethyl group and a trifluoroethyl group with a 4-fluorophenyl moiety. L-Cysteine, S-(cyclopropylmethyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]- may have potential applications in medicinal chemistry due to its unique structure and potential biological activities. Further research is needed to investigate its pharmacological properties and potential therapeutic uses.

Upstream product

• 124-38-9 carbon dioxide 
• 1408001-09-1 potassium (R,Z)-3-((cyclopropylmethyl)thio)-2-((2,2,2-trifluoro-1-(4-fluorophenyl)ethylidene)-amino)propanoate 
• 655-32-3 2,2,2-trifluoro-1-(4-fluorophenyl)ethanone 
• 880762-37-8 2(R)-[2,2,2-trifluoro-1(S)-(4-fluorophenyl)ethylamino]-3-tritylsulfanyl-propionic acid 
• 7051-34-5 cyclopropylcarbinyl bromide 

Downstream Products

• 849094-11-7 (R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)amino)propanoic acid 
• 1310340-58-9 (S)-N-cyclopropyl-3-((R)-3-(cyclopropylmethylsulfonyl)-2-((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethylamino)propanamido)-2-oxopentanamide 
• 1408001-11-5 (3S)-N-cyclopropyl-3-((R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)-ethyl)amino)propanamido)-2-hydroxypentanamide 

Relevant articles and documents

CATHEPSIN INHIBITORS FOR THE TREATMENT OF BONE CANCER AND BONE CANCER PAIN

The present invention is directed to methods of using compounds that are inhibitors of cysteine proteases, in particular, of both cathepsins S and K and optionally further cathepsins B and/or L in treating bone cancer. The present invention is directed to pharmaceutical compositions comprising these compounds for treating bone cancer and bone cancer pain, especially the pain associated with metastasis. A single compound can be used to ameliorate the pain, the injury to bone, while also reducing tumor growth, the risk of metastasis and/or invasiveness of the cancer.