881676-32-0

Basic information

• Product Name: 1H-Pyrrole-3-carboxaldehyde, 5-broMo-
• Synonyms: 1H-Pyrrole-3-carboxaldehyde, 5-broMo-;5-BroMo-1H-Pyrrole-3-carboxaldehyde;5-BroMo-1H-pyrrole-3-carbaldehyde;1H-Pyrrole-3-carbaldehyde,5-broMo-
• CAS NO: 881676-32-0
• Molecular Formula: C₅H₄BrNO
• Molecular Weight: 173.99536
• EINECS: -0
• Mol File: 881676-32-0.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 299.6±20.0 °C(Predicted)
• Appearance: /
• Density: 1.819±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 14.52±0.50(Predicted)
• CAS DataBase Reference: 1H-Pyrrole-3-carboxaldehyde, 5-broMo-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-carboxaldehyde, 5-broMo-(881676-32-0)
• EPA Substance Registry System: 1H-Pyrrole-3-carboxaldehyde, 5-broMo-(881676-32-0)

Safety Data

• Hazardous Substances Data: 881676-32-0(Hazardous Substances Data)

Usage

General Description

1H-Pyrrole-3-carboxaldehyde, 5-bromo- is a chemical compound with the molecular formula C5H3BrNO. It is an aldehyde derivative of pyrrole, which is a five-membered aromatic heterocyclic compound. The presence of the bromine atom at the 5-position of the pyrrole ring gives this compound unique chemical and physical properties. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Additionally, it has potential applications in the field of materials science and as a building block in organic chemistry reactions. Due to its reactivity and versatile nature, 1H-Pyrrole-3-carboxaldehyde, 5-bromo- is a valuable compound for use in various research and industrial applications.

Upstream product

• 7126-39-8 pyrrole-3-carboxaldehyde 
• 881674-99-3 methyl 5-bromo-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxylate 
• 2703-17-5 methyl 1H-pyrrole-3-carboxylate 
• 16420-39-6 methyl 5-bromo-1H-pyrrole-3-carboxylate 
• 71803-59-3 3-hydroxymethyl-1H-pyrrole 
• 37964-17-3 pyrrole-3-carboxylic acid ethyl ester 
• 931-03-3 1H-pyrrole-3-carboxylic acid 

Downstream Products

• 928324-87-2 5-[2-(methylthio)phenyl]-1H-pyrrole-3-carbaldehyde 
• 881677-48-1 2-[(2-bromo-4-formyl-1H-pyrrol-1-yl)sulfonyl]benzonitrile 
• 928324-88-3 5-(2-bromophenyl)-1H-pyrrole-3-carbaldehyde 
• 881674-56-2 5-(2-fluorophenyl)-1H-pyrrole-3-carboxaldehyde 
• 1055304-81-8 1-(4-chloro-5-(2-fluoropyridin-3-yl)-1-{[3-(methylsulfonyl)phenyl]sulfonyl}-1H-pyrrol-3-yl)-N-methylmethanamine fumarate 
• 1055304-75-0 1-(5-(2-fluoropyridin-3-yl)-1-{[3-(methylsulfonyl)phenyl]sulfonyl}-1H-pyrrol-3-yl)-N-methylmethanamine fumarate 
• 1055305-46-8 3-({2-(2-chloropyridin-3-yl)-4-[(methylamino)methyl]-1H-pyrrol-1-yl}sulfonyl)benzonitrile fumarate 
• 1055304-87-4 3-{1-[(3-fluorophenyl)sulfonyl]-4-[(methylamino)methyl]-1H-pyrrol-2-yl}pyridine-2-carbonitrile fumarate 
• 1055304-89-6 1-{5-(2-fluoropyridin-3-yl)-1-[(3-methoxyphenyl)sulfonyl]-1H-pyrrol-3-yl}-N-methylmethanamine fumarate 
• 1055304-71-6 1-{1-[(2-fluorophenyl)sulfonyl]-5-(2-fluoropyridin-3-yl)-1H-pyrrol-3-yl}-N-methylmethanamine fumarate 
• 1055305-04-8 1-{1-[(2,3-difluorophenyl)sulfonyl]-5-(2-fluoropyridin-3-yl)-1H-pyrrol-3-yl}-N-methylmethanamine hydrochloride 
• 1055305-06-0 1-{1-[(3-fluoro-4-methylphenyl)sulfonyl]-5-(2-fluoropyridin-3-yl)-1H-pyrrol-3-yl}-N-methylmethanamine hydrochloride 
• 1055304-90-9 1-{1-[(3-fluorophenyl)sulfonyl]-5-(2-fluoropyridin-3-yl)-1H-pyrrol-3-yl}-N-methylmethanamine hydrochloride 
• 1055306-50-7 tert-butyl ({1-[(2,3-difluorophenyl)sulfonyl]-5-(2-fluoropyridin-3-yl)-1H-pyrrol-3-yl}methyl)methylcarbamate 

Relevant articles and documents

Identification, characterization, synthesis of major metabolites biotransformed from vonoprazan fumarate

A first synthetic research concerning four observed metabolites and their deuterium-labeled analogues of reflux esophagitis drug vonoprazan fumarate is reported. Among which the synthetic methods of three metabolites M ? I, M-III, M-IV-Sul, and four stable isotop labeled analogues M-I-d4, M-II-d4, M-III-d4, M-IV-Sul-d4 have not yet been reported before. The structures of these compounds were elucidated on the basis of MS and NMR spectroscopy.

Polycyclic amide derivative as CDK9 inhibitor, and preparation method and application thereof

The invention belongs to the technical field of polycyclic amide derivatives, and particularly relates to a polycyclic amide derivative as a CDK9 inhibitor, and a preparation method and application thereof. The polycyclic amide derivative shows excellent CDK9 enzyme inhibitory activity, and can be used for preparing drugs for treating cancers, especially hematologic cancers including acute myeloid leukemia, multiple myeloma, chronic lymphocytic leukemia, follicular lymphoma and the like and solid tumors, such as acute myeloid leukemia, multiple myeloma, chronic lymphocytic leukemia and follicular lymphoma, including breast cancer, prostate cancer, ovarian cancer, hepatocellular carcinoma, pancreatic cancer, kidney cancer, stomach cancer, colorectal cancer, lung cancer and the like.

Application of 2-aryl substituted pyrrole compound in medicine for killing biomphalarid snails

The invention relates to an application of 2-aryl substituted pyrrole compound in a medicine for killing biomphalarid snails and belongs to the technical field of prevention and treatment of bilharziasis, and particularly provides the chemical structure of the 2-aryl substituted pyrrole compound and a preparation method of same. The 2-aryl substituted pyrrole compound, being an active component, is used for preparing the snail killing agent in the forms of suspending agents, emulsions and micro-emulsions for killing the biomphalarid snail. Immersion killing use amount of the 2-aryl substitutedpyrrole compound being the active component of the snail killing agent is 0.5-10.00 mg/l, and immersion killing time is 24-72 h. Experiment proves that the 2-aryl substituted pyrrole compound has killing activity on the biomphalarid snails and is lower than a snail killing agent, niclosamide, in the prior art in toxicity on aquatic organisms. The compound can be processed to prepare the snail killing agents and applied in the field of prevention and treatment of bilharziasis.