88229-25-8Relevant academic research and scientific papers
A metal-free tandem ring-opening/ring-closing strategy for the heterocyclic conversion of benzoxazin-4-ones to oxazolines
Rajesh, Nomula,Manisha, Banala,Ranjith, Jala,Krishna, Palakodety Radha
, p. 6058 - 6064 (2016/02/03)
A facile metal-free tandem ring-opening/ring-closing strategy was developed for the synthesis of oxazolines in good to excellent reaction yields under mild reaction conditions. This reaction essentially describes a novel tool for the heterocyclic conversi
Iodine(III)-promoted synthesis of oxazolines from N-allylamides
Moon, Nicholas G.,Harned, Andrew M.
supporting information, p. 2960 - 2963 (2013/06/27)
PhI(OAc)2 (activated by BF3·OEt2) has been used to promote the oxidative cyclization of N-allylamides to give oxazolines. The reaction products are formed in high yield and, when a branched allylic amine is used, high diastereoselectivity. Initial mechanistic experiments suggest that the final C-O bond is formed from a reactive tight ion pair, rather than a neutral external nucleophile.
POTENTIAL CENTRAL NERVOUS SYSTEM ACTIVE AGENTS. 3. SYNTHESIS OF SOME SUBSTITUTED BENZAMIDES AND PHENYLACETAMIDES.
Agwada
, p. 231 - 235 (2007/10/02)
The preparation and special properties (IR, **1H NMR) are given for 45 benzamides and 10 phenylacetamides substituted on nitrogen with allyl, benzhydryl, benzyl, or cyclopropyl groups, and variously substituted on the acyl part with halo, methoxyl, methyl, or nitro groups. The benzamide derivatives were synthesized by the Schotten-Baumann method, and the phenylacetamide derivatives were prepared by heating the appropriate N-benzhydrylammonium salt in o-xylene. Thirty-one of the compounds are new.
