882872-58-4Relevant academic research and scientific papers
Practical method for the synthesis of (R)-homopipecolinic acid and (R)-homoproline esters from ω-chloroalkanoic acids and available chiral amines
Hashimoto, Norio,Funatomi, Takashi,Misaki, Tomonori,Tanabe, Yoo
, p. 2214 - 2223 (2007/10/03)
A practical synthesis of (R)-homopipecolinic acid methyl ester 1 and (R)-homoproline methyl ester 2 was performed utilizing (i) a direct intramolecular cyclization of ω-chloro-β-enamino esters 11 and 12, which were prepared from available (S)-1-phenylethy
