171730-95-3 Usage
Description
(R)-Homopipecolic acid methyl ester, also known as (R)-HPME, is a chiral chemical compound belonging to the class of homopipecolic acid derivatives. It is characterized by its specific (R) configuration, which plays a crucial role in its potential pharmaceutical applications. (R)-HPME has demonstrated promising biological activities, such as interactions with neurotransmitter receptors and enzymes, indicating its potential therapeutic benefits. Its unique structure and properties make it a valuable target for further research and development in the creation of new drugs.
Uses
Used in Pharmaceutical Applications:
(R)-Homopipecolic acid methyl ester is used as a pharmaceutical compound for its potential therapeutic benefits. Its interactions with neurotransmitter receptors and enzymes suggest that it may be utilized in the development of new drugs targeting various medical conditions.
Used in Drug Discovery and Development:
(R)-HPME is used as a research compound in drug discovery and development. Its unique structure and properties make it an attractive candidate for further investigation, potentially leading to the creation of novel therapeutic agents.
Used in Neurotransmitter Receptor Research:
(R)-Homopipecolic acid methyl ester is used as a research tool in the study of neurotransmitter receptors. Its interactions with these receptors can provide valuable insights into the development of drugs targeting neurological and psychiatric disorders.
Used in Enzyme Research:
(R)-HPME is also used in enzyme research, where its interactions with various enzymes can contribute to the understanding of enzyme function and the development of enzyme-targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 171730-95-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,1,7,3 and 0 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 171730-95:
(8*1)+(7*7)+(6*1)+(5*7)+(4*3)+(3*0)+(2*9)+(1*5)=133
133 % 10 = 3
So 171730-95-3 is a valid CAS Registry Number.
171730-95-3Relevant articles and documents
INTRAMOLECULAR CYCLIZATION OF ω-PRIMARY AMINO ELECTROPHILIC OLEFINS TO FUNCTIONALIZED PYRROLIDINES AND PIPERIDINES.
Knouzi, N.,Vaultier, M.,Toupet, L.,Carrie, R.
, p. 1757 - 1760 (1987)
The intramolecular 1,4-Michael type addition of in situ chemoselectively generated primary amines bearing an electrophilic double bond in the ω position leads to functionalized pyrrolidines and piperidines under very mild conditions.
Convenient multigram synthesis of (R)-homopipecolic acid methyl ester
Breuning, Matthias,Steiner, Melanie
, p. 1386 - 1389 (2006)
(R)-Homopipecolic acid methyl ester has been prepared on a multigram scale from 3,4-dihydro-2H-pyran in five steps and 36% overall yield. The stereochemistry was introduced via an asymmetric Michael addition and a fractional crystallization. Georg Thieme
HEPATITIS B CORE PROTEIN MODULATORS
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Page/Page column 106, (2018/04/13)
The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound of formula:
NEW ANTIBACTERIAL COMPOUNDS
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Page/Page column 79, (2014/03/21)
The present invention is related to novel compounds of formula (I) that may inhibit the activity of the FabI enzyme, and which are useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compound
