88303-56-4

Upstream product

• 6770-15-6 1,4-dichloro-5-hydroxy-9,10-anthracenedione 
• 100-39-0 benzyl bromide 

Downstream Products

• 88303-59-7 2-<2-<(2-hydroxyethyl)amino>ethyl>-5-<<2-<(2-hydroxyethyl)amino>ethyl>amino>-7-(phenylmethoxy)anthra<1,9-cd>pyrazol-6(2H)-one 
• 88303-62-2 2-<2-<(2-hydroxyethyl)amino>ethyl>-5-<<2-<(2-hydroxyethyl)amino>ethyl>amino>-10-(phenylmethoxy)anthra<1,9-cd>pyrazol-6(2H)-one 
• 88303-60-0 7-hydroxy-2-{2-[(2-hydroxyethyl)amino]ethyl}-5-({2-[(2-hydroxyethyl)amino]ethyl}amino)anthra(1,9-cd)pyrazol-6(2H)-one 
• 88303-61-1 losoxantrone 
• 109921-38-2 5-<<2-<(2-hydroxyethyl)amino>ethyl>amino>-2-<2-<(2-hydroxyethyl)(phenylmethyl)amino>ethyl>-7-(phenylmethoxy)anthra<1,9-cd>pyrazol-6(2H)-one 
• 438201-60-6 1,4-diamino-5-(phenylmethoxy)-9,10-anthracenedione 
• 438201-61-7 6-amino-8-(phenylmethoxy)-7H-benzo[e]perimidin-7-one 
• 438201-62-8 6-amino-11-(phenylmethoxy)-7H-benzo[e]perimidin-7-one 
• 88303-57-5 5-chloro-2-<2-<(2-hydroxyethyl)amino>ethyl>-7-(phenylmethoxy)anthra<1,9-cd>pyrazol-6(2H)-one 
• 88303-58-6 5-chloro-2-<2-<(2-hydroxyethyl)amino>ethyl>-10-(phenylmethoxy)anthra<1,9-cd>pyrazol-6(2H)-one 
• 109921-36-0 5-chloro-2-<2-<(2-hydroxyethyl)(phenylmethyl)amino>ethyl>-7-(phenylmethoxy)anthra<1,9-cd>pyrazol-6(2H)-one 
• 109921-37-1 5-chloro-2-<2-<(2-hydroxyethyl)(phenylmethyl)amino>ethyl>-10-(phenylmethoxy)anthra<1,9-cd>pyrazol-6(2H)-one 

Relevant academic research and scientific papers

Anticancer anthrapyrazoles. Improved syntheses of clinical agents CI-937, CI-941, and piroxantrone hydrochloride

Improved processes for the synthesis of bulk quantities of the anthrapyrazole clinical agents CI-937, CI-941, and piroxantrone hydrochloride are reported. Reported also are detailed analytical and spectroscopic data for these agents and intermediates of t

Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones

An improved process for producing anthra[1,9-cd]-pyrazol-6(2H)-ones from 1,4-dichloro-5,8-disubstituted 9,10-anthracenediones. The process produces higher yields by using a new combination of protecting groups on the compounds which allows for easier and cleaner chromatographic resolution. The compounds produced have antibacterial, antifungal, antileukemic, and antitumor activity.