88313-91-1Relevant articles and documents
From Azido Acids to Macrolactams and Macrolactones
Bartra, Marti,Bou, Valenti,Garcia, Jordi,Urpi, Felix,Vilarrasa, Jaume
, p. 270 - 272 (2007/10/02)
A new method is reported for the conversion of azido acids into lactams, via thioester formation and in situ azide reduction and cyclisation under high-dilution conditions; since the quantitative conversion of macrolactams to macrolactones has been shown to be feasible, this results in an indirect, alternative macrolactonisation procedure.