88357-16-8Relevant academic research and scientific papers
COMPOUNDS AND METHOD OF USE
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Paragraph 1038, (2019/09/06)
This present disclosure relates to compounds with ferroptosis inducing activity, a method of treating a subject with cancer with the compounds, and combination treatments with a second therapeutic agent.
Bismuth(III)-Promoted Acetylation of Thioethers into Thioacetates
Jevric, Martyn,Petersen, Anne Ugleholdt,Mans?, Mads,Madsen, Anders,Nielsen, Mogens Br?ndsted
, p. 4675 - 4688 (2015/08/03)
The thioacetate group is extensively employed as an anchoring group for attachment of molecules onto gold surfaces or between electrodes in molecular electronics. On account of its ready hydrolysis, it is often incorporated in the last step of a synthetic
Copper-free sonogashira coupling reaction using a trans-spanning 1,2-Bis(2-thienylethynyl)benzene ligand
Atobe, Shingo,Sonoda, Motohiro,Suzuki, Yuki,Shinohara, Hiroyuki,Yamamoto, Takuya,Ogawa, Akiya
supporting information; experimental part, p. 980 - 982 (2012/02/01)
Novel copper-free Sonogashira coupling reaction of aryl halides with terminal acetylenes proceeded in the presence of 1,2-bis(2-thienylethynyl) benzene (1) as a trans-bidentatable ligand.
Novel cruciform structures as model compounds for coordination induced single molecule switches
Grunder, Sergio,Huber, Roman,Wu, Songmei,Schoenenberger, Christian,Calame, Michel,Mayor, Marcel
, p. 140 - 144 (2011/08/04)
We have synthesized various molecular cruciforms consisting of two different crossing π-systems and comprising crosswise arranged thiol- and pyridine-anchor groups. With these model compounds we strive towards the investigation of a new switching concept based on the potential dependent coordination of pyridines to gold electrodes in an electrochemical set-up. Integration of these cruciform molecules between both electrodes of a mechanically controlled break junction in a liquid environment gave insight into their single molecule transport properties. These studies allowed individual transport characteristics to be assigned to the bar subunits of the cruciforms but also revealed the remaining experimental challenges to realize the suggested switching concept. Schweizerische Chemische Gesellschaft.
Iron-catalyzed thioetherification of thiols with aryl iodides
Wu, Jhih-Ru,Lin, Che-Hung,Lee, Chin-Fa
supporting information; experimental part, p. 4450 - 4452 (2009/12/29)
FeCl3 in combination with bisphosphine ligands represents an efficient catalyst system for the cross-coupling of aryl- and alkyl thiols with aryl iodides, a broad spectrum of functional groups can be tolerated during the catalysis. The Royal Society of Chemistry 2009.
Synthesis and serotonin transporter activity of sulphur-substituted α-alkyl phenethylamines as a new class of anticancer agents
Cloonan, Suzanne M.,Keating, John J.,Butler, Stephen G.,Knox, Andrew J.S.,Jorgensen, Anne M.,Peters, Guenther H.,Rai, Dilip,Corrigan, Desmond,Lloyd, David G.,Williams, D. Clive,Meegan, Mary J.
scheme or table, p. 4862 - 4888 (2010/01/16)
The discovery that some serotonin reuptake transporter (SERT) ligands have the potential to act as pro-apoptotic agents in the treatment of cancer adds greatly to their diverse pharmacological application. 4-Methylthioamphetamine (MTA) is a selective ligand for SERT over other monoamine transporters. In this study, a novel library of structurally diverse 4-MTA analogues were synthesised with or without N-alkyl and/or C-α methyl or ethyl groups so that their potential SERT-dependent antiproliferative activity could be assessed. Many of the compounds displayed SERT-binding activity as well as cytotoxic activity. While there was no direct correlation between these two effects, a number of derivatives displayed anti-tumour effects in lymphoma, leukaemia and breast cancer cell lines, showing further potential to be developed as possible chemotherapeutic agents.
Palladium-catalyzed carbon-sulfur cross-coupling reactions with indium tri(organothiolate) and its application to sequential one-pot processes
Lee, Jae-Young,Phil, Ho Lee
supporting information; experimental part, p. 7413 - 7416 (2009/05/07)
(Chemical Equation Presented) It was found that indium tri(organothiolate) is an effective nucleophilic coupling partner in Pd-catalyzed C-S cross-coupling reactions to produce the functionalized sulfides in excellent yields with high atom efficiency and
Two-photon absorbing materials with quenched emission
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Page/Page column 6, (2009/01/20)
The present invention provides substituted phenanthroline compounds with high two photon absorption cross sections, as well as substituted phenanthroline compounds which additionally have quenched fluorescence emission upon two photon absorption.
New cruciform structures: Toward coordination induced single molecule switches
Grunder, Sergio,Huber, Roman,Horhoiu, Viviana,Gonzalez, Maria Teresa,Schoenenberger, Christian,Calame, Michel,Mayor, Marcel
, p. 8337 - 8344 (2008/03/11)
(Chemical Equation Presented) New cruciform structures 1-4 were synthesized to investigate a new single molecule switching mechanism arising from the interplay between the molecule and the electrode surface. These molecular cruxes consist of two rod-type
Fabrication of steady junctions consisting of α, ωbis(thioacetate) oligo(p-phenylene vinylene)s in nanogap electrodes
Liang, Tien-Tzu,Naitoh, Yasuhisa,Horikawa, Masayo,Ishida, Takao,Mizutani, Wataru
, p. 13720 - 13726 (2007/10/03)
For obtaining molecular devices using metal-molecule-metal junctions, it is necessary to fabricate a steady conductive bridge-structure; that is stable chemical bonds need to be established from a single conductive molecule to two facing electrodes. In th
