88440-83-9

Upstream product

• 1696-17-9 N,N-diethylbenzamide 
• 106-95-6 allyl bromide 
• 76041-86-6 2-bromo-N,N-diethylbenzamide 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 
• 35466-83-2 allyl methyl carbonate 

Downstream Products

• 99618-31-2 N,N-diethyl-o-<3-(trimethylsilyl)allyl>benzamide 
• 134-32-7 1-amino-naphthalene 
• 17496-14-9 2,3-dihydro-2-methyl-1H-inden-1-one 
• 90-15-3 α-naphthol 

Relevant academic research and scientific papers

Direct allylation of aromatic and α,β-unsaturated carboxamides under ruthenium catalysis

The ruthenium-catalyzed oxidative allylation of aromatic and α,β-unsaturated carboxamides with allylic carbonates is described. These transformations proceed readily with complete linear γ-selectivity of substituted allylic carbonates. the Partner Organisations 2014.

Mild rhodium(III)-catalyzed direct C-H allylation of arenes with allyl carbonates

All(yl) possible! A rhodium(III)-catalyzed intermolecular direct C-H allylation reaction utilizing readily accessible allyl carbonates was developed. This method allows the allylation of electron-neutral arenes, providing complete γ-selectivity, high isomeric ratio, good substrate scope, and excellent functional group compatibility. Copyright

Selective halogen - Magnesium exchange reaction via organomagnesium ate complex

Halogen-magnesium exchange of various aryl halides is achieved with a magnesium ate complex at low temperatures. Tributylmagnesate (nBu3MgLi) induces facile iodine-magnesium exchange at -78 °C. Dibutylisopropylmagnesate (iPrnBu2MgLi) is more reactive than nBu3MgLi, and this reagent accomplishes selective bromine-magnesium exchange at -78 °C. This procedure is utilized for the preparation of various polyfunctionalized arylmagnesium species. The exchange of alkenyl halides using this method proceeds with retention of configuration of the double bond.

Ortho-metalated aromatic tertiary amides: New synthetic applications

Ortho-lithio-cuprate species derived from aromatic tertiary amides exhibited a significantly larger field of application than the lithio precursor.

Regioselective ortho-alkylation of N,N-diethylbenzamides via lithiation and copper transmetalation

One-pot ortho-lithiation and copper transmetalation with CuCN*LiCl of N,N-diethylbenzamides afford the corresponding aryl cyanocuprate, which gives coupling with some aliphatic halides in fair to good yields.