88485-94-3

Basic information

• Product Name: (naphthalen-1-ylamino)(phenyl)acetonitrile
• CAS NO: 88485-94-3
• Molecular Formula: C₁₈H₁₄N₂
• Molecular Weight: 258.3172
• Mol File: 88485-94-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 453.6°C at 760 mmHg
• Flash Point: 228.1°C
• Density: 1.205g/cm³
• Vapor Pressure: 2.04E-08mmHg at 25°C
• Refractive Index: 1.698
• CAS DataBase Reference: (naphthalen-1-ylamino)(phenyl)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (naphthalen-1-ylamino)(phenyl)acetonitrile(88485-94-3)
• EPA Substance Registry System: (naphthalen-1-ylamino)(phenyl)acetonitrile(88485-94-3)

Safety Data

• Hazardous Substances Data: 88485-94-3(Hazardous Substances Data)

Usage

General Description

"(Naphthalen-1-ylamino)(phenyl)acetonitrile" is a chemical compound with the formula C18H14N2. It is a nitrile derivative with a naphthalene and phenyl group attached to the amino and nitrile functional groups, respectively. (naphthalen-1-ylamino)(phenyl)acetonitrile is often used in chemical research and synthesis as a building block for the creation of more complex molecules. It may also have potential applications in the pharmaceutical industry, as nitrile-containing compounds are of interest for their diverse biological activities. However, as with any chemical, proper handling and safety precautions should be observed due to its potential toxic or hazardous properties.

Upstream product

• 532-28-5 (RS)-mandelonitrile 
• 134-32-7 1-amino-naphthalene 
• 151-50-8 potassium cyanide 
• 100-52-7 benzaldehyde 
• 7677-24-9 trimethylsilyl cyanide 
• 108-88-3 toluene 
• 890-51-7 N-benzylidenenaphthalen-1-amine 

Relevant articles and documents

A unique combination of KI/ZnFe2O4 as a catalyst for oxidative Strecker reaction

α-Aminonitriles as key intermediates for the preparation of α-amino acid derivatives, amides, diamines, peptides, proteins and heterocycles were synthesized through methylarene oxidation in the Strecker reaction using a unique combination of KI/ZnFe2O4 as the best catalyst and aqueous tert-butyl hydroperoxide as oxidant. A wide range of amines and methylarenes were converted to the corresponding products. Operational simplicity, short reaction time and recyclability of the catalyst are advantages of this protocol.

One-pot three-component synthesis of α-aminonitriles using potassium hexacyanoferrate(II) as an eco-friendly cyanide source

An efficient and environmentally friendly method has been developed for the synthesis of α-aminonitriles via one-pot three-component condensation of carbonyl compounds, amines, and potassium hexacyanoferrate(II) in the presence of benzoyl chloride as a promoter. This protocol has the features of use of eco-friendly cyanide source, high yield, and simple work-up procedure.

Synthesis and pharmacological activities of arylarylamino- and aryl-aryliminoacetonitriles

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