88550-19-0

Usage

Uses

Used in Medical Diagnostics:
2-(methoxymethyl)benzoic acid serves as a biomarker for the detection of neuroblastoma, a cancer that affects nerve cells. Its presence in biological samples can indicate the presence of this type of cancer, aiding in early diagnosis and treatment planning.
Used in Neurotransmitter Metabolism Research:
2-(methoxymethyl)benzoic acid is utilized in research related to the metabolism of catecholamines, which are neurotransmitters involved in various physiological processes including stress response and mood regulation. Studying 2-(methoxymethyl)benzoic acid can provide insights into the metabolic pathways and potential therapeutic targets for conditions related to neurotransmitter imbalances.
Used in Pharmaceutical Synthesis:
2-(methoxymethyl)benzoic acid is employed as a precursor in the synthesis of certain pharmaceuticals. Its unique chemical structure makes it a valuable building block for developing new drugs, particularly those targeting neurological conditions or requiring specific metabolic properties.
Used in the Food and Beverage Industry:
As a derivative of vanillin, 2-(methoxymethyl)benzoic acid may also find applications in the food and beverage industry for flavor enhancement, given its potential to contribute to the taste profile of various products.

Upstream product

• 87-41-2 2-benzofuran-1(3H)-one 
• 77-78-1 dimethyl sulfate 
• 612-20-4 2-(hydroxymethyl)benzoic acid 
• 74-88-4 methyl iodide 
• 124-41-4 sodium methylate 
• 7115-91-5 2-ethoxycarbonylbenzyl bromide 
• 57991-54-5 2-(methoxymethyl)benzonitrile 
• 52711-30-5 1-bromo-2-(methoxymethyl)benzene 
• 109-72-8 n-butyllithium 
• 60-29-7 diethyl ether 
• 538-86-3 benzyl methyl ether 

Downstream Products

• 1092768-74-5 C₂₅H₃₀ClNO₄ 
• 942-57-4 methyl 2-(methoxymethyl)benzoate 
• 408535-88-6 (2-methoxymethyl-phenyl)-acetonitrile 
• 171055-42-8 2-methoxymethylbenzyl bromide 
• 68718-99-0 α-chloro-α'-methoxy-o-xylene 
• 4385-35-7 isochroman-3-one 
• 87-41-2 2-benzofuran-1(3H)-one 
• 62172-88-7 2-(methoxymethyl)-benzyl alcohol 

Relevant academic research and scientific papers

Birch Reductive Alkylation of Methyl m-(Hydroxymethyl)benzoate Derivatives and the Behavior of o- and p-(Hydroxymethyl)benzoates under Reductive Alkylation Conditions

Birch reductive alkylation of methyl m-(hydroxymethyl)benzoate derivatives, using lithium in ammonia-tetrahydrofuran in the presence of tertbutyl alcohol, can be achieved without significant loss of benzylic oxygen substituents. Similar treatment of o- and p-(hydroxymethyl)benzoate derivatives results largely in loss of benzylic oxygen substituents. The results are rationalized by computations describing electron density patterns in the putative radical anion intermediate involved in these reactions.

Benzohydroxamic acids as potent and selective anti-HCV agents

A diverse collection of 40 derivatives of benzohydroxamic acid (BHAs) of various structural groups were synthesized and tested against hepatitis C virus (HCV) in full-genome replicon assay. Some of these compounds demonstrated an exceptional activity, suppressing viral replication at sub-micromolar concentrations. The compounds were inactive against key viral enzymes NS3, and NS5B in vitro assays, suggesting host cell inhibition target(s). The testing results were consistent with metal coordination by the BHAs hydroxamic group in complex with a target(s). Remarkably, this class of compounds did not suppress poliomyelitis virus (PV) propagation in RD cells indicating a specific antiviral activity of BHAs against HCV.