885702-66-9

Upstream product

• 864512-14-1 2-iodophenyl 4-chlorobenzenesulfonate 
• 17154-34-6 (trimethylsilyl)diphenylphosphine 
• 108-90-7 chlorobenzene 
• 17763-67-6 Phenyl triflate 
• 829-85-6 diphenylphosphane 
• 583-55-1 1-Bromo-2-iodobenzene 
• 75-77-4 chloro-trimethyl-silane 
• 62336-24-7 (2-bromophenyl)diphenylphosphane 
• 106865-17-2 (2-bromophenyl)-di(o-tolyl)phosphine borane 

Relevant academic research and scientific papers

Small Gold(I) and Gold(I)–Silver(I) Clusters by C?Si Auration

Auration of o-trimethylsilyl arylphosphines leads to the formation of gold and gold–silver clusters with ortho-metalated phosphines displaying 3c–2e Au?C?M bonds (M=Au/Ag). Hexagold clusters [Au6L4](X)2 are obtained by reaction of (L?TMS)AuCl with AgX, whereas reaction with AgX and Ag2O leads to gold–silver clusters [Au4Ag2L4](X)2. Oxo-trigold(I) species [Au3O]+ were identified as the intermediates in the formation of the silver-doped clusters. Other [Au5], [Au4Ag], and [Au12Ag4] clusters were also obtained. Clusters containing PAu?Au?AuP structural motif display good catalytic activity in the activation of alkynes under homogeneous conditions.

New Hindered Amide Base for Aryne Insertion into Si-P, Si-S, Si-N, and C-C Bonds

A general method for a new, hindered lithium diadamantylamide (LDAM) base-promoted insertion of arynes into Si-P, Si-S, Si-N, and C-C bonds is described. Arynes are generated from easily available aryl triflates and halides. Subsequent reaction of the aryne with silylated phosphines, sulfides, or amines affords the insertion products. Furthermore, a one-step synthesis of anthracenes from aryl halides and aryl ketones is also demonstrated. Cyano, aryl, alkyl, trifluoromethyl, vinyl, methoxy, chloro, fluoro, and even formyl moieties are compatible with the reaction conditions. The new lithium amide affords higher yields compared with lithium tetramethylpiperidide (LiTMP)-promoted reactions. Furthermore, the bulkiness of LDAM base essentially suppresses aryne reaction with base, allowing use of aryl halides and triflates as the limiting reagents.

Effect of silylated triarylphosphine ligands on rhodium-catalyzed hydrosilylation

A series of silylated triarylphosphines was synthesized. Hydrosilylation reactions of styrene with triethoxysilane catalyzed by RhCl3/silylated triarylphosphine complexes were investigated. The complexes RhCl3/phenylbis(4-trimethylsilylphenyl)phosphine and RhCl3/tris(4-trimethylsilylphenyl)phosphine exhibited higher activity as well as greater β-adduct selectivity, and no unsaturated product was obtained. The results suggest that the silyl moieties have a significant impact on the catalytic process. Copyright

Ortho-Trialkylstannyl Arylphosphanes by C-P and C-Sn Bond Formation in Arynes

A novel and efficient approach to ortho-trialkylstannyl arylphosphanes by the reaction of arynes generated in situ with stannylated phosphanes (R3Sn-PR2) is described. Concurrent C-P and C-Sn bond formation occurs with high yields, and stannylated products are easily transformed into valuable ortho-substituted arylphosphanes. The reaction features high efficiency, good regioselectivity, and excellent practicality.

Effect of triarylphosphane ligands on the rhodium-catalyzed hydrosilylation of alkene

A series of triarylphosphanes (1a, 2a, 3a, 4a, 5a, 6a, 7a, 8a, 9a, 10a, 11a) have been synthesized. An X-ray crystal structure analysis of (2-bromophenyl)diphenylphosphane (1a) unambiguously confirmed the constitution of the functionalized phosphane. The hydrosilylation reaction of styrene with triethoxysilane catalyzed with RhCl3/triarylphosphane was studied. In comparison with the classic Wilkinson's catalyst, rhodium complexes with functionalized triarylphosphane ligands are characterized by a very high catalytic effectiveness for the hydrosilylation of alkene. Among these catalysts tested, RhCl3/diphenyl(2-(trimethylsilyl)phenyl)phosphane (8a) exhibited excellent catalytic properties. Using this silicon-containing phosphane ligand for the rhodium-catalyzed hydrosilylation of styrene, both higher conversion of alkene and higher β-adduct selectivity were obtained than with Wilkinson's catalyst.

P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS

The present invention relates to novel P-chirogenic organophosphorus compounds of general formula (I). The present invention also provides a process for the synthesis of said compounds of formula (I). The present invention also relates to intermediate products of general formulae (II), (III) and (IV), as shown below, which are involved in the synthesis of compounds (I). Further, the invention relates to metal complexes comprising compounds (I) as ligands. The novel compounds and complexes of the present invention are useful in asymmetric catalysis by transition metal complexes or organocatalysis, especially for asymmetric hydrogenation or allylation. Compounds of general formula (I) may useful as agrochemical and therapeutic substances, or as reagents or intermediates for fine chemistry.