886469-23-4

Basic information

• Product Name: PEG9-Tos
• Synonyms: PEG9-Tos;Tos-PEG8-OH
• CAS NO: 886469-23-4
• Molecular Formula: C₂₃H₄₀O₁₁S
• Molecular Weight: 524.6221
• Mol File: 886469-23-4.mol

Chemical Properties

• Appearance: /
• Solubility: Soluble in Water, DMSO, DCM, DMF
• CAS DataBase Reference: PEG9-Tos(CAS DataBase Reference)
• NIST Chemistry Reference: PEG9-Tos(886469-23-4)
• EPA Substance Registry System: PEG9-Tos(886469-23-4)

Safety Data

• Hazardous Substances Data: 886469-23-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
PEG9-Tos is used as a versatile building block for organic synthesis, particularly in the creation of biocompatible polymers and other complex organic molecules. Its hydrophilic PEG spacer and hydroxyl group facilitate the attachment of various functional groups, making it a valuable component in the synthesis of pharmaceuticals, biomaterials, and other specialty chemicals.
Used in Drug Delivery Systems:
In the pharmaceutical industry, PEG9-Tos is used as a component in drug delivery systems to improve the solubility, stability, and bioavailability of therapeutic agents. The PEG spacer can be used to attach drug molecules or other targeting moieties, enhancing the overall performance of the drug delivery system.
Used in Bioconjugation:
PEG9-Tos is utilized as a linker in bioconjugation processes, where it serves to covalently attach biologically active molecules, such as peptides, proteins, or nucleic acids, to other molecules or surfaces. The hydroxyl group and tosyl leaving group enable efficient conjugation, while the PEG spacer provides steric stabilization and reduces immunogenicity or non-specific interactions.
Used in Surface Modification:
In materials science, PEG9-Tos is employed for surface modification of various substrates, including nanoparticles, polymers, and other surfaces. The PEG spacer and hydroxyl group allow for the attachment of PEGylated layers, which can improve the biocompatibility, reduce protein adsorption, and enhance the stability of the modified surfaces.
Used in Cosmetics and Personal Care:
In the cosmetics and personal care industry, PEG9-Tos is used as an ingredient to improve the solubility and stability of active ingredients, as well as to provide moisturizing and conditioning effects. The hydrophilic nature of the PEG spacer and the ability to derivatize the hydroxyl group make it suitable for a wide range of cosmetic formulations.

Upstream product

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Downstream Products

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Relevant articles and documents

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