886510-09-4 Usage
Uses
Used in Pharmaceutical Industry:
3-Fluoro-2-trifluoromethyl-isonicotinic acid is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical industry, 3-fluoro-2-trifluoromethyl-isonicotinic acid is utilized as a building block for the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their performance and selectivity, leading to more effective crop protection.
Used in Materials Science:
3-Fluoro-2-trifluoromethyl-isonicotinic acid is also employed in the field of materials science for the development of new materials with specific properties. Its unique structure can contribute to the creation of materials with improved characteristics, such as enhanced stability, reactivity, or selectivity.
Used in Drug Discovery:
Due to its potential biological activity, 3-fluoro-2-trifluoromethyl-isonicotinic acid is used in drug discovery research. It serves as a valuable starting point for the development of new drugs, particularly in the areas of medicinal chemistry and pharmaceutical research, where its unique properties can be harnessed to create novel therapeutic agents.
Overall, 3-fluoro-2-trifluoromethyl-isonicotinic acid is a versatile and valuable chemical intermediate with diverse applications across various industries, including pharmaceuticals, agrochemicals, materials science, and drug discovery. Its unique structure and potential biological activity make it an essential component in the development of innovative and effective products.
Check Digit Verification of cas no
The CAS Registry Mumber 886510-09-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,5,1 and 0 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 886510-09:
(8*8)+(7*8)+(6*6)+(5*5)+(4*1)+(3*0)+(2*0)+(1*9)=194
194 % 10 = 4
So 886510-09-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H3F4NO2/c8-4-3(6(13)14)1-2-12-5(4)7(9,10)11/h1-2H,(H,13,14)
886510-09-4Relevant articles and documents
Preparation method of 2-trifluoromethyl-3-fluoro-4-picolinic acid and derivatives thereof
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, (2020/04/17)
The invention discloses a preparation method of 2-trifluoromethyl-3-fluoro-4-picolinic acid and derivatives thereof, and is characterized in that provided is the preparation method of 2-trifluoromethyl-3-fluoro-4-picolinic acid and the derivatives thereof by a method of introducing trifluoromethyl into 2-site of a polysubstituted pyridine ring through a free radical mechanism, wherein the preparation method is suitable for large-scale application. The method for directly carrying out trifluoromethylation reaction on the 2-site of 3-fluoro-4-pyridine carboxylic acid alkyl ester is reported forthe first time, and is simple and convenient in process, easily available in raw materials, high in conversion rate and simple in reaction post-treatment operation. Meanwhile, the selectivity of the method in introducing trifluoromethyl into the 2-site of pyridine is quite high, and a single product with trifluoromethyl substituted at the 2-site can be obtained only through simple recrystallization.
Synthesis method of 3-fluoro-2-trifluoromethyl isonicotinic acid
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, (2020/01/12)
The invention discloses a synthesis method of a fluorine-containing heterocyclic compound medical intermediate. The method comprises the following steps: (1) taking 2-chloro-3-nitropyridine as a raw material to carry out reacting with trifluoromethyltrimethylsilane in dimethyl formamide (DMF) under catalysis of cuprous iodide and 1,10-phenanthroline to obtain 2-trifluoromethyl-3-nitropyridine; (2)carrying out a reflux reaction on the obtained 2-trifluoromethyl-3-nitropyridine in tetrabutylammonium fluoride by using acetonitrile, dimethyl sulfoxide (DMSO) or DMF as a solvent to obtain 2-trifluoromethyl-3-fluoropyridine; and (3) removing hydrogen from the obtained 2-trifluoromethyl-3-fluoropyridine under action of a lithium reagent, and introducing dry carbon dioxide gas to obtain the 3-fluoro-2-trifluoromethyl isonicotinic acid. The method has the advantages of high product yield, high operability, environmental friendliness, high safety factor and the like.
