886510-21-0 Usage
Description
3-Fluoro-2-trifluoromethylpyridine is an organic compound characterized by the presence of a fluorine atom at the 3-position and a trifluoromethyl group at the 2-position on a pyridine ring. This unique molecular structure endows it with specific chemical properties that make it a valuable intermediate in the synthesis of various pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
3-Fluoro-2-trifluoromethylpyridine is used as a reagent for the synthesis of thieno-pyrimidine compounds, which possess fungicidal activity. This makes it a valuable component in the development of antifungal medications, contributing to the treatment and prevention of fungal infections.
Additionally, 3-Fluoro-2-trifluoromethylpyridine is used as a key intermediate in the production of 3-azabicyclo[3.1.0]hexane-6-carboxylic acid amide derivatives. These derivatives function as somatostatin receptor subtype 4 (SSTR4) agonists, playing a crucial role in the regulation of various physiological processes. The development of SSTR4 agonists has significant implications in the treatment of medical conditions such as neuroendocrine tumors and other related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 886510-21-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,5,1 and 0 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 886510-21:
(8*8)+(7*8)+(6*6)+(5*5)+(4*1)+(3*0)+(2*2)+(1*1)=190
190 % 10 = 0
So 886510-21-0 is a valid CAS Registry Number.
886510-21-0Relevant articles and documents
Deoxofluorination of (Hetero)aromatic Acids
Alekseenko, Anatoliy N.,Bugera, Maksym Ya.,Gerus, Igor I.,Kiriakov, Oleksandr,Klipkov, Anton A.,Mykhailiuk, Pavel K.,Pustovit, Yurii,Razhyk, Bohdan,Semenov, Sergey,Starova, Viktoriia S.,Tananaiko, Oksana Yu.,Tarasenko, Karen,Tolmachev, Andrei A.,Trofymchuk, Serhii,Zaporozhets, Olga A.
, p. 3110 - 3124 (2020/03/23)
Diverse trifluoromethyl-substituted compounds were synthesized by deoxofluorination of cinnamic and (hetero)aromatic carboxylic acids with sulfur tetrafluoride. The obtained products were used as starting materials in the preparation of novel fluorinated amino acids, anilines, and aliphatic amines - valuable building blocks for medicinal chemistry and agrochemistry.
