887267-34-7

Basic information

• Product Name: 2,4,5-TRIFLUOROTOLUENE
• Synonyms: 1-Methyl-2,4,5-trifluorobenzene;1,2,4-Trifluoro-5-methylbenzene;2,4,5-TRIFLUOROTOLUENE
• CAS NO: 887267-34-7
• Molecular Formula: C7H5F3
• Molecular Weight: 146.11
• Product Categories: Halogen toluene
• Mol File: 887267-34-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 121.9°C at 760 mmHg
• Flash Point: 24.1°C
• Appearance: Colorless to pale yellow/Liquid
• Density: 1.234g/cm³
• Vapor Pressure: 17.2mmHg at 25°C
• Refractive Index: 1.437
• CAS DataBase Reference: 2,4,5-TRIFLUOROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,5-TRIFLUOROTOLUENE(887267-34-7)
• EPA Substance Registry System: 2,4,5-TRIFLUOROTOLUENE(887267-34-7)

Safety Data

• Hazardous Substances Data: 887267-34-7(Hazardous Substances Data)

Usage

General Description

2,4,5-Trifluorotoluene is a chemical compound with the molecular formula C7H5F3. It is a colorless liquid that is widely used as a solvent in various industrial processes, including the production of pharmaceuticals and polymers. 2,4,5-Trifluorotoluene is also used as an intermediate in the synthesis of other chemicals and can be found in some consumer products. It is considered to have low acute toxicity, but its long-term effects on human health and the environment are not well-studied. Additionally, 2,4,5-Trifluorotoluene is a volatile organic compound and can contribute to air pollution. Due to its industrial uses and potential environmental impacts, the handling and disposal of 2,4,5-Trifluorotoluene should be carefully regulated to minimize potential harm.

InChI:InChI=1/C7H5F3/c1-4-2-6(9)7(10)3-5(4)8/h2-3H,1H3

Upstream product

• 875664-57-6 4,5-difluoro-2-methylaniline 
• 127371-50-0 1,2-difluoro-4-methyl-5-nitrobenzene 
• 7494-45-3 1,2-dichloro-4-methyl-5-nitrobenzene 

Relevant articles and documents

Preparation method of 2,4,5-trifluorophenylacetic acid

The invention belongs to the technical field of preparation of drug intermediates, and discloses a preparation method of 2,4,5-trifluorophenylacetic acid, wherein the preparation method comprises the steps: step 1, reacting raw materials, a quaternary ammonium salt catalyst, sulfolane and potassium fluoride to obtain a first intermediate; step 2, carrying out hydrogenation catalytic reaction on the first intermediate to obtain a second intermediate; step 3, carrying out salt forming reaction on the second intermediate and a fluorinating reagent, quenching, and carrying out diazotization reaction on the second intermediate and a sodium nitrite aqueous solution to obtain diazonium salt; step 4, carrying out high-temperature cracking on the diazonium salt, to obtain 2,4,5-trifluorotoluene; and step 5 to step 7, carrying out halogenation, cyanidation and hydrolysis reactions on 2,4,5-trifluorotoluene in sequence, and thus obtaining 2,4,5-trifluorophenylacetic acid. The raw materials adopted by the method are easy to obtain and low in cost, the yield of the corresponding product obtained in each step is high, and large-scale production of the 2,4,5-trifluorophenylacetic acid is facilitated.