887267-34-7 Usage
Uses
Used in Pharmaceutical Industry:
2,4,5-Trifluorotoluene is used as a solvent in the production of pharmaceuticals for its ability to dissolve a wide range of substances, facilitating various chemical reactions and processes in drug manufacturing.
Used in Polymer Industry:
In the polymer industry, 2,4,5-Trifluorotoluene is utilized as a solvent to aid in the synthesis and processing of polymers, enhancing their properties and performance in various applications.
Used as a Chemical Intermediate:
2,4,5-Trifluorotoluene serves as an intermediate in the synthesis of other chemicals, contributing to the production of a variety of compounds used in different industries.
Used in Consumer Products:
Although its presence may be limited, 2,4,5-Trifluorotoluene can be found in some consumer products, where it may be used for specific applications due to its unique chemical properties.
Environmental Considerations:
Given its status as a volatile organic compound, 2,4,5-Trifluorotoluene can contribute to air pollution. Therefore, its use and disposal must be carefully managed to reduce environmental impacts and potential harm to human health.
Check Digit Verification of cas no
The CAS Registry Mumber 887267-34-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,7,2,6 and 7 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 887267-34:
(8*8)+(7*8)+(6*7)+(5*2)+(4*6)+(3*7)+(2*3)+(1*4)=227
227 % 10 = 7
So 887267-34-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H5F3/c1-4-2-6(9)7(10)3-5(4)8/h2-3H,1H3
887267-34-7Relevant academic research and scientific papers
Preparation method of 2,4,5-trifluorophenylacetic acid
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Paragraph 0040; 0043-0044; 0056-0068; 0083, (2021/05/29)
The invention belongs to the technical field of preparation of drug intermediates, and discloses a preparation method of 2,4,5-trifluorophenylacetic acid, wherein the preparation method comprises the steps: step 1, reacting raw materials, a quaternary ammonium salt catalyst, sulfolane and potassium fluoride to obtain a first intermediate; step 2, carrying out hydrogenation catalytic reaction on the first intermediate to obtain a second intermediate; step 3, carrying out salt forming reaction on the second intermediate and a fluorinating reagent, quenching, and carrying out diazotization reaction on the second intermediate and a sodium nitrite aqueous solution to obtain diazonium salt; step 4, carrying out high-temperature cracking on the diazonium salt, to obtain 2,4,5-trifluorotoluene; and step 5 to step 7, carrying out halogenation, cyanidation and hydrolysis reactions on 2,4,5-trifluorotoluene in sequence, and thus obtaining 2,4,5-trifluorophenylacetic acid. The raw materials adopted by the method are easy to obtain and low in cost, the yield of the corresponding product obtained in each step is high, and large-scale production of the 2,4,5-trifluorophenylacetic acid is facilitated.
