887604-05-9

Upstream product

• 2834-00-6 2-pentadecyn-1-ol 
• 4292-19-7 1-Iodododecane 
• 18202-13-6 pentadec-14-yn-1-ol 
• 100-39-0 benzyl bromide 
• 112-53-8 1-dodecyl alcohol 
• 505-52-2 brassylic acid 
• 116754-58-6 13-bromo-1-tridecylalcohol 
• 13362-52-2 1,13-tridecanediol 
• 1216963-74-4 lithium acetylide-ethylenediamine complex 
• 887604-02-6 (((13-bromotridecyl)oxy)methyl)benzene 

Downstream Products

• 887604-10-6 2-(15-Benzyloxy-pentadec-1-ynyl)-1,4-dimethoxy-benzene 
• 75736-52-6 [16,16,16-2H₃]-hexadecanol 
• 887604-30-0 Q₃FA₁₅ 
• 903577-47-9 2-(15-Hydroxypentadecyl)benzene-1,4-diol 
• 887604-25-3 15-(2,5-dimethoxyphenyl)pentadecan-1-ol 
• 887604-20-8 1-(15-Benzyloxy-pentadec-1-ynyl)-2,3,4,5-tetramethoxy-benzene 
• 887604-15-1 1-(15-Benzyloxy-pentadec-1-ynyl)-2,4,5-trimethoxy-benzene 

Relevant academic research and scientific papers

NUCLEOSIDE PRODRUGS AND USES RELATED THERETO

Disclosed are acyclic nucleoside prodrugs with improved metabolic stability and oral bioavailability. In general, the prodrugs are derivatives of acyclic nucleoside phosphonates containing a lipid-like moiety that can increase oral absorption and subsequent stability in the liver and plasma. Preferably, the lipid-like moiety can resist enzyme-mediated ω-oxidation, such as ω -oxidation catalyzed by cytochrome P450 enzymes. Also disclosed are pharmaceutical formulations of the acyclic nucleoside prodrugs. The acyclic nucleoside prodrugs and pharmaceutical formulations thereof can be used to treat viral infections, such as HIV infections, and/or viral-associated cancer, such as HPV-associated cancers.

Quinol fatty alcohols as promoters of axonal growth

The synthesis of three series of quinol fatty alcohols (QFAs) and their biological activities on the promotion of axonal growth are described. Interestingly, the 15-(2,5-dimethoxyphenyl)pentadecan-1-ol, the QFA bearing 15 carbon atoms on the side chain (n = 15), shows the most potent promotion of axonal growth in the presence of both permissive and non-permissive naturally occurring substrates such as Sema3A and myelin proteins.