889107-93-1

Basic information

• Product Name: Benzoic acid, 2-[3-[[(1,1-dimethylethoxy)carbonyl]amino]propoxy]-4-(1,1-dimethylethyl) -, methyl ester
• CAS NO: 889107-93-1
• Molecular Formula: C20H31NO5
• Molecular Weight: 365.47
• Mol File: 889107-93-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-[3-[[(1,1-dimethylethoxy)carbonyl]amino]propoxy]-4-(1,1-dimethylethyl) -, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-[3-[[(1,1-dimethylethoxy)carbonyl]amino]propoxy]-4-(1,1-dimethylethyl) -, methyl ester(889107-93-1)
• EPA Substance Registry System: Benzoic acid, 2-[3-[[(1,1-dimethylethoxy)carbonyl]amino]propoxy]-4-(1,1-dimethylethyl) -, methyl ester(889107-93-1)

Safety Data

• Hazardous Substances Data: 889107-93-1(Hazardous Substances Data)

Upstream product

• 21003-83-8 methyl 4-tert-butyl-2-hydroxybenzoate 
• 83948-53-2 3-bromopropylamine tert-butylcarbamate 
• 161398-79-4 3-tert-butyl-1-(methoxymethoxy)benzene 
• 585-34-2 3-tert-butylphenyol 
• 852370-27-5 4-tert-butyl-2-(methoxymethoxy)benzoic acid 
• 58885-58-8 N-tert-butoxycarbonyl-3-aminopropanol 

Downstream Products

• 889107-94-2 2-(3-tert-butoxycarbonylaminopropoxy)-4-tert-butylbenzoic acid 
• 889123-72-2 2-[2-(3-tert-butoxycarbonylaminopropoxy)-4-tert-butylbenzoylamino]-N-(5-chloropyridin-2-yl)benzamide 

Relevant articles and documents

Anthranilamide inhibitors of factor Xa

SAR about the B-ring of a series of N2-aroyl anthranilamide factor Xa (fXa) inhibitors is described. B-ring o-aminoalkylether and B-ring p-amine probes of the S1′ and S4 sites, respectively, afforded picomolar fXa inhibitors that performed well in in vitro anticoagulation assays.

ANTITHROMBOTIC DIAMIDES

This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt of the compound) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor.