889129-00-4Relevant academic research and scientific papers
HEPARAN SULFATE SYNTHESIS
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Page/Page column 28; 56, (2010/11/03)
The invention provides an efficient modular chemical synthesis for heparan sulfate oligosaccharides based on orthogonal protection strategies. Modular disaccharide building blocks, themselves the product of a novel combinatorial synthesis, are combined in
Modular synthesis of heparan sulfate oligosaccharides for structure-activity relationship studies
Arungundram, Sailaja,Al-Mafraji, Kanar,Asong, Jinkeng,Leach III, Franklin E.,Amster, I. Jonathan,Venot, Andre,Turnbull, Jeremy E.,Boons, Geert-Jan
supporting information; experimental part, p. 17394 - 17405 (2010/03/23)
Although hundreds of heparan sulfate binding proteins have been identified and implicated in a myriad of physiological and pathological processes, very little information is known about the ligand requirements for binding and mediating biological activiti
Synthesis of saponins with cholestanol, cholesterol, and friedelanol as aglycones
Schimmel, Joerg,Eleuterio, M. Ines Passos,Ritter, Gerd,Schmidt, Richard R.
, p. 1701 - 1721 (2007/10/03)
Procedures for the synthesis of branched Xylss(1→3)[Galss- (1→2)]-Glc and Xylss(1→3)[Galss(1→2)]-GlcUA trisaccharides ss-linked to the 3-O of cholesterol, cholestanol, and friedelanol, respectively, were developed. To this end, ss-selective glucosylation
Synthesis of N-glycan oxazolines: donors for endohexosaminidase catalysed glycosylation
Rising, Thomas W.D.F.,Claridge, Timothy D.W.,Davies, Nicola,Gamblin, David P.,Moir, James W.B.,Fairbanks, Antony J.
, p. 1574 - 1596 (2007/10/03)
Oxazoline mono-, di-, tri- and hexasaccharides, corresponding to the core components of N-linked glycoprotein high mannose glycans, are synthesised as potential glycosyl donors for endohexosaminidase catalysed glycosylation of glycopeptides and glycoprote
