890027-95-9

Upstream product

• 147200-10-0 (3S,5R)-dihydro-5-hydroxymethyl-3-methyl-2(3H)-furanone 
• 147200-08-6 (3S,5R)-5-(tert-butyldiphenylsilyloxymethyl)-3-methyl-dihydrofuran-2(3H)-one 
• 189884-53-5 2-methyl-2-(3-phenyl-2-propenyl)malonic acid dimethyl ester 
• 115362-50-0 (3S,5R)-4,5-dihydro-5-iodomethyl-3-methyl-2(3H)-furanone 
• 890027-35-7 (3S,5R)-5-(tert-butyldiphenylsilanyloxymethyl)-2-[(E)-(3S)-3-methoxymethoxymethyl-3-methyl-6-trimethylsilanyl-hex-4-enyl]-3-methyltetrahydrofuran-2-ol 
• 890027-50-6 (R)-acetic acid 4-hydroxy-2-methoxymethoxymethyl-2-methylbutyl ester 
• 890028-20-3 (+)-tert-butyl-[(2R,4S,5R,6R,7S)-7-methoxymethoxymethyl-4,7-dimethyl-6-vinyl-1-oxaspiro[4.4]non-2-ylmethoxy]diphenylsilane 
• 890027-74-4 (E)-(R)-acetic acid 2-methoxymethoxymethyl-2-methyl-5-phenylpent-4-enyl ester 
• 890027-86-8 (S,E)-3-((methoxymethoxy)methyl)-3-methyl-6-(trimethylsilyl)hex-4-en-1-ol 
• 890027-87-9 (S,E)-(6-iodo-4-((methoxymethoxy)methyl)-4-methylhex-2-enyl)trimethylsilane 
• 890027-72-2 (E)-(R)-2-methoxymethoxymethyl-2-methyl-5-phenylpent-4-enoic acid methyl ester 
• 890027-47-1 (S,E)-2-((methoxymethoxy)methyl)-2-methyl-5-phenylpent-4-en-1-ol 
• 890027-41-5 (R)-2-methyl-2-(3-phenyl-2-propenyl)malonic acid monomethyl ester 
• 890027-44-8 (E)-(R)-2-hydroxymethyl-2-methyl-5-phenylpent-4-enoic acid methyl ester 

Downstream Products

• 890028-03-2 (+)-3,5-dinitrobenzoic acid (2R,4S,5R,6R,7S)-6-(2-hydroxyethyl)-7-methoxymethoxymethyl-4,7-dimethyl-1-oxaspiro[4.4]non-2-ylmethyl ester 
• 890028-05-4 (+)-3,5-dinitrobenzoic acid (2R,4S,5R,6R,7S)-7-methoxymethoxymethyl-4,7-dimethyl-6-(2-oxoethyl)-1-oxaspiro[4.4]non-2-ylmethyl ester 

Relevant academic research and scientific papers

Synthetic studies on (+)-ophiobolin A: Asymmetric synthesis of the spirocyclic CD-ring moiety

Asymmetric synthesis of the spirocyclic CD-ring moiety of (+)-ophiobolin A is described. Fragment A, which was prepared via pig liver esterase (PLE)-mediated kinetic resolution, and fragment B, which was prepared via diastereoselective allylation and subs