890027-72-2Relevant academic research and scientific papers
Synthetic studies on (+)-ophiobolin A: Asymmetric synthesis of the spirocyclic CD-ring moiety
Noguchi, Naoyoshi,Nakada, Masahisa
, p. 2039 - 2042 (2006)
Asymmetric synthesis of the spirocyclic CD-ring moiety of (+)-ophiobolin A is described. Fragment A, which was prepared via pig liver esterase (PLE)-mediated kinetic resolution, and fragment B, which was prepared via diastereoselective allylation and subs
Enantioselective total synthesis of (+)-ophiobolin A
Tsuna, Kazuhiro,Noguchi, Naoyoshi,Nakada, Masahisa
, p. 5476 - 5486 (2013/06/05)
The enantioselective total synthesis of (+)-ophiobolin A is described. This total synthesis features the construction of the spiro CD ring of (+)-ophiobolin A through a stereoselective intramolecular Hosomi-Sakurai cyclization reaction, the joining of the
