89129-66-8 Usage
Uses
Used in Pharmaceutical Industry:
Methyl-4,4-difluoroacetoacetate (MeDFAA) is used as a key intermediate in the synthesis of pharmaceutical compounds for the development of new drugs and therapeutic agents.
Used in Chemical Research:
Methyl-4,4-difluoroacetoacetate (MeDFAA) is used as a research reagent for the preparation of organic compounds, enabling scientists to explore new chemical reactions and pathways in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 89129-66-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,1,2 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 89129-66:
(7*8)+(6*9)+(5*1)+(4*2)+(3*9)+(2*6)+(1*6)=168
168 % 10 = 8
So 89129-66-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H6F2O3/c1-10-4(9)2-3(8)5(6)7/h5H,2H2,1H3
89129-66-8Relevant academic research and scientific papers
PROCESS FOR THE PREPARATION OF 4,4-DIFLUORO-3-OXOBUTANOIC ACID ESTERS
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Page/Page column 7-8, (2010/02/15)
The present invention relates to a process for the preparation of a compound of the formula (I), wherein R is C1-12 alkyl, by the contact of a compound of the general formula (II) , wherein R1 and R2 are each, independently, C1-12 alkyl; or R1 and R2 join together with the nitrogen atom to which they are attached to form an alicyclic amine ring containing 4 to 7 carbon atoms or a morpholine ring, with an acetic acid ester of the general formula (III) CH3COOR, wherein R is as defined under formula (I), in the presence of a base.