892869-52-2 Usage
Derivative of oleanolic acid
2-(Hydroxyimino)-3-oxo-olean-12-en-28-oic acid phenylmethyl ester is a chemical compound that is derived from oleanolic acid, a natural triterpenoid found in many plants.
Potential pharmacological properties
This compound has potential pharmacological properties and has been studied for its anti-inflammatory and anti-cancer effects.
Inhibits cancer cell growth
The compound has been shown to inhibit the growth of cancer cells, making it a potential candidate for the development of new drugs for cancer.
Reduces inflammation
2-(Hydroxyimino)-3-oxo-olean-12-en-28-oic acid phenylmethyl ester has also been shown to reduce inflammation, making it a potential candidate for the development of new drugs for inflammatory diseases.
Enhanced stability and bioavailability
The phenylmethyl ester form of the compound may enhance its stability and bioavailability, making it a promising candidate for further research and development in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 892869-52-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,2,8,6 and 9 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 892869-52:
(8*8)+(7*9)+(6*2)+(5*8)+(4*6)+(3*9)+(2*5)+(1*2)=242
242 % 10 = 2
So 892869-52-2 is a valid CAS Registry Number.
InChI:InChI=1/C37H51NO4/c1-32(2)17-19-37(31(40)42-23-24-11-9-8-10-12-24)20-18-35(6)25(26(37)21-32)13-14-29-34(5)22-27(38-41)30(39)33(3,4)28(34)15-16-36(29,35)7/h8-13,26,28-29,41H,14-23H2,1-7H3/t26-,28-,29+,34-,35+,36+,37-/m0/s1
892869-52-2Relevant articles and documents
Methyl 1,2-shift rearrangement on c-ring and decarboxylation at C28 of oleanolic acid derivatives
Hu, Jun,Wu, Jindan,Ju, Yong
, p. 133 - 136 (2014/03/21)
A new oleanolic acid derivative with A-ring lactone, C-ring rearrangement and decarboxylation at C28 was synthesized, which was confirmed by HRMS, NMR and X-ray crystal structure. It is the first report about the methyl rearrangement on C-ring of oleanoli
Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase
Chen, Jun,Liu, Jun,Zhang, Luyong,Wu, Guanzhong,Hua, Weiyi,Wu, Xiaoming,Sun, Hongbin
, p. 2915 - 2919 (2007/10/03)
Oleanolic acid and its synthetic derivatives have been identified as novel inhibitors of glycogen phosphorylase. Within this series of compounds, 4 (IC50 = 3.3 μM) is the most potent GPa inhibitor. Preliminary structure-activity relationships of the oleanolic acid derivatives are discussed.
